Troponin I Type 3 (cardiac) Antibody

Images

 
Western Blot: Troponin I Type 3 (cardiac) Antibody [NBP2-20735] - Sample (50 ug of whole cell lysate) A: Mouse Heart, 12% SDS PAGE gel, diluted at 1:10000.
Western Blot: Troponin I Type 3 (cardiac) Antibody [NBP2-20735] - Sample (30 ug of whole cell lysate) A: A431 B: Molt-4 12% SDS PAGE gel, diluted at 1:1000.

Order Details


    • Catalog Number
      NBP2-20735
    • Availability
      Product Discontinued

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Troponin I Type 3 (cardiac) Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Cardiac Troponin I. The exact sequence is proprietary.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TNNI3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:20000
Theoretical MW
24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Troponin I Type 3 (cardiac) Antibody

  • Cardiac troponin I
  • CMD1FF
  • CMD2A
  • CMH7MGC116817
  • cTnI
  • familial hypertrophic cardiomyopathy 7
  • RCM1
  • TNNC1troponin I, cardiac
  • troponin I type 3 (cardiac)
  • troponin I, cardiac muscle

Background

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Additional Troponin I Type 3 (cardiac) Products

Bioinformatics Tool for Troponin I Type 3 (cardiac) Antibody (NBP2-20735)

Discover related pathways, diseases and genes to Troponin I Type 3 (cardiac) Antibody (NBP2-20735). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Troponin I Type 3 (cardiac) Antibody (NBP2-20735)

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Research Areas for Troponin I Type 3 (cardiac) Antibody (NBP2-20735)

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Blogs on Troponin I Type 3 (cardiac).

Troponin I Type 3 (TnI, cardiac)
Troponin I is part of a heteromeric thin filament regulatory complex that governs skeletal and cardiac muscle contraction. Troponin I is composed of three subunits: troponin I (TnI), troponin T (TnT), and troponin C (TnC), and each of these components...  Read full blog post.

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Bioinformatics

Gene Symbol TNNI3
Uniprot