Troponin I Type 3 (cardiac) Antibody

Images

 
Western Blot: Troponin I Type 3 (cardiac) Antibody [H00007137-D01P] - Analysis of TNNI3 expression in transfected 293T cell line by TNNI3 polyclonal antibody.Lane 1: TNNI3 transfected lysate(24.00 KDa).Lane 2: ...read more

Order Details


    • Catalog Number
      H00007137-D01P
    • Availability
      Product Discontinued

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Troponin I Type 3 (cardiac) Antibody Summary

Immunogen
TNNI3 (AAH96165.1, 1 a.a. - 210 a.a.) full-length human protein. MADGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTEKENREVGDWRKNIDALSGMEGRKKKFES
Specificity
TNNI3 - troponin I type 3 (cardiac),
Clonality
Polyclonal
Host
Rabbit
Gene
TNNI3
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Troponin I Type 3 (cardiac) Antibody

  • Cardiac troponin I
  • CMD1FF
  • CMD2A
  • CMH7MGC116817
  • cTnI
  • familial hypertrophic cardiomyopathy 7
  • RCM1
  • TNNC1troponin I, cardiac
  • troponin I type 3 (cardiac)
  • troponin I, cardiac muscle

Background

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Additional Troponin I Type 3 (cardiac) Products

Bioinformatics Tool for Troponin I Type 3 (cardiac) Antibody (H00007137-D01P)

Discover related pathways, diseases and genes to Troponin I Type 3 (cardiac) Antibody (H00007137-D01P). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Troponin I Type 3 (cardiac) Antibody (H00007137-D01P)

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Pathways for Troponin I Type 3 (cardiac) Antibody (H00007137-D01P)

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Blogs on Troponin I Type 3 (cardiac).

Troponin I Type 3 (TnI, cardiac)
Troponin I is part of a heteromeric thin filament regulatory complex that governs skeletal and cardiac muscle contraction. Troponin I is composed of three subunits: troponin I (TnI), troponin T (TnT), and troponin C (TnC), and each of these components...  Read full blog post.

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Bioinformatics

Gene Symbol TNNI3
Entrez
Uniprot