TrkC Antibody

Images

 
Western Blot: TrkC Antibody [NBP1-78032] - HEK293 cells (Lane 2, arrowhead). Lane 1 is a non-transfected control. Cell extracts were resolved by electrophoresis and transferred to nitrocellulose. The membrane was probed ...read more
Western Blot: TrkC Antibody [NBP1-78032] - Lane 1 is wild-type cortex lysate, Lane 2 is Tamalin knock-out cortex lysate, and Lane 3 isTrkC knock-out cortex lysate. The membrane was probed with the primary antibody at a ...read more
Western Blot: TrkC Antibody [NBP1-78032] - detect endogenous TrkC in mouse cortex lysate (Lane 1). Lane 2 is TrkC knock-out cortex lysate. Cell extracts were resolved by electrophoresis and transferred to ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-78032
    • Availability
      Product Discontinued

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TrkC Antibody Summary

Immunogen
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the carboxyl terminus of mouse TrkC protein.
Specificity
This affinity purified antibody is directed against mouse TrkC protein.A BLAST analysis was used to suggest cross-reactivity with TrkC protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NTRK3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:10000
  • ELISA 1:5000-1:20000
  • Immunoprecipitation 1 ug
Application Notes
This affinity purified antibody has been tested for use in ELISA and western blotting. While the predicted molecular weight for TrkCT1 is approximately 70 kDa, the protein has been reported - migrate at about 95 kDa on western blots. The molecular weight noted for TrkCT1 depends somewhat upon the cell lysate or extract used for western blotting, and this variation may be Due to post-translational modifications of the protein.

Reactivity Notes

Cross reactivity with TrkC from other sources has not been tested.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative
0.01% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TrkC Antibody

  • EC 2.7.10
  • EC 2.7.10.1
  • ETS related protein-neurotrophic receptor tyrosine kinase fusion protein
  • ETV6-NTRK3 fusion
  • gp145(trkC)
  • GP145-TrkC
  • Neurotrophic tyrosine kinase receptor type 3
  • neurotrophic tyrosine kinase, receptor, type 3
  • NT 3 receptor
  • NT-3 growth factor receptor
  • NTRK3
  • TrkC tyrosine kinase
  • TrkC
  • trk-C
  • TRKCneurotrophin 3 receptor
  • tyrosine kinase receptor C

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics Tool for TrkC Antibody (NBP1-78032)

Discover related pathways, diseases and genes to TrkC Antibody (NBP1-78032). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for TrkC Antibody (NBP1-78032)

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Research Areas for TrkC Antibody (NBP1-78032)

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Blogs on TrkC.

TrkB: Bridging Ontogenesis and Oncogenesis
Tropomyosin receptor kinase B (TrkB) is a member of the Trk receptor tyrosine kinases family consisting of TrkA, TrkB and TrkC. The sequence of these family members is highly conserved. Interaction of brain-derived neurotrophic factor (BDNF) with its...  Read full blog post.

TrkB: Docking for Neurotrophins and Beyond.
Tropomyosin receptor kinase B (TrkB) is a member of the Trk receptor tyrosine kinases family consisting of TrkA, TrkB and TrkC. The sequence of these family members is highly conserved. TrK's are activated by several neurotrophins, which are small pro...  Read full blog post.

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Bioinformatics

Gene Symbol NTRK3
Entrez
Uniprot