TRIM5 alpha Antibody


Western Blot: TRIM5 alpha Antibody [NBP1-47111] - analysis of TRIM5a expression in human stomach (A), thymus (B), and uterus (C) cell lysate with anti-TRIM5a at 2 ug /ml.
Immunocytochemistry/ Immunofluorescence: TRIM5 alpha Antibody [NBP1-47111] - of TRIM5a in human breast tissue with anti-TRIM5a at 10 ug/ml.

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TRIM5 alpha Antibody Summary

Rabbit anti-TRIM5a polyclonal antibody was raised against a synthetic peptide corresponding to amino acids near the C-terminus of rhesus monkey TRIM5a (Genbank accession No. AAS48505).
IgG purified
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  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000

Reactivity Notes


Packaging, Storage & Formulations

Store at 4C. Do not freeze.
0.02% Sodium Azide
IgG purified

Alternate Names for TRIM5 alpha Antibody

  • EC 6.3.2
  • EC 6.3.2.-
  • RING finger protein 88
  • RNF88tripartite motif protein TRIM
  • TRIM5alpha
  • tripartite motif containing 5
  • tripartite motif protein TRIM5
  • tripartite motif-containing 5
  • tripartite motif-containing protein 5


TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Gene Symbol TRIM5