TRIF/TICAM1 Antibody Summary
Antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human TRIF. The immunogen is located within the last 50 amino acids of TRIF.
Ion exchange chromatography
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Western Blot 1:100-1:2000
- ELISA 1:100-1:2000
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Paraffin 1:10-1:500
- Immunofluorescence 10 ug/ml
TRIF antibody can be used for detection of TRIF by Western blot at 2 to 4 mg/ml.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Ion exchange chromatography
Alternate Names for TRIF/TICAM1 Antibody
- Proline-rich, vinculin and TIR domain-containing protein B
- PRVTIRBTIR domain-containing adapter protein inducing IFN-beta
- Putative NF-kappa-B-activating protein 502H
- TICAM-1TIR domain containing adaptor inducing interferon-beta
- TIR domain-containing adapter molecule 1
- TIR domain-containing adaptor molecule 1
- toll-like receptor adaptor molecule 1
- TRIFToll-interleukin-1 receptor domain-containing adapter protein inducinginterferon beta
TRIF is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TRIF, along with other molecules such as TIRP, TIRAP, and MyD88, serves as an adaptor protein to several of the TLR molecules. Following activation of TLR3 and TLR4, TRIF engages the kinase TBK1 and allows its subsequent activation of the interferon regulatory factor (IRF)-3. TRIF is also involved in the activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappaB.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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Publications for TRIF/TICAM1 Antibody (NBP1-77221)(1)
Showing Publication 1 - 1
|Publication using NBP1-77221
| Shi CS, Kehrl JH. MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages. J Biol Chem. 2008 Nov 28 [PMID: 18772134]
WB (mouse RAW264.7 cells), Fig. 2F; 3B,C; 4A,B,F. MyD88 and Trif target Beclin1 to trigger autophagy in macrophages. Shi C, J kehrl. JBCdoi:10.1074/jbc.M804478200 (2008). WB (mouse RAW264.7 cells), Fig. 2F; 3B,C; 4A,B,F.
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