TRIF/TICAM1 Antibody

Images

 
Western Blot: TRIF/TICAM1 Antibody [NBP1-77221] - Analysis of TRIF in human lung lysate with TRIF antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry-Paraffin: TRIF/TICAM1 Antibody [NBP1-77221] - Human lung tissue with TRIF antibody at 10 ug/ml.
Western Blot: TRIF/TICAM1 Antibody [NBP1-77221] - Human lung cell lysates with TRIF antibody at (A) 2 and (B) 4 ug/ml.
Immunofluorescence: TRIF/TICAM1 Antibody [NBP1-77221] - Immunofluorescence of TRIF in Human Lung cells with TRIF antibody at 10 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC, IHC-P, ICC, IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

TRIF/TICAM1 Antibody Summary

Immunogen
Antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human TRIF. The immunogen is located within the last 50 amino acids of TRIF.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TICAM1
Purity
Ion exchange chromatography
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunocytochemistry
  • Immunofluorescence 10 ug/ml
Application Notes
TRIF antibody can be used for detection of TRIF by Western blot at 2 to 4 mg/ml.
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
TRIF/TICAM1 Peptide (NBP1-77221PEP)
Publications
Read Publication using NBP1-77221.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Ion exchange chromatography

Alternate Names for TRIF/TICAM1 Antibody

  • MGC35334
  • Proline-rich, vinculin and TIR domain-containing protein B
  • PRVTIRBTIR domain-containing adapter protein inducing IFN-beta
  • Putative NF-kappa-B-activating protein 502H
  • TICAM1
  • TICAM-1TIR domain containing adaptor inducing interferon-beta
  • TIR domain-containing adapter molecule 1
  • TIR domain-containing adaptor molecule 1
  • toll-like receptor adaptor molecule 1
  • TRIF
  • TRIFToll-interleukin-1 receptor domain-containing adapter protein inducinginterferon beta

Background

TRIF is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TRIF, along with other molecules such as TIRP, TIRAP, and MyD88, serves as an adaptor protein to several of the TLR molecules. Following activation of TLR3 and TLR4, TRIF engages the kinase TBK1 and allows its subsequent activation of the interferon regulatory factor (IRF)-3. TRIF is also involved in the activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappaB.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TRIF/TICAM1 Antibody (NBP1-77221)(1)

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Secondary Antibodies

 

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Bioinformatics Tool for TRIF/TICAM1 Antibody (NBP1-77221)

Discover related pathways, diseases and genes to TRIF/TICAM1 Antibody (NBP1-77221). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on TRIF/TICAM1.

TRIF/TICAM1 and mitochondrial dynamics in the innate immune response
TRIF, also known as toll like receptor adaptor molecule 1 or TICAM1, is known for its role in invading foreign pathogens as part of our innate immune response. TRIF/TICAM1 is a TIR-domain adaptor protein (toll/interleukin-1 receptor) that interacts...  Read full blog post.

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Bioinformatics

Gene Symbol TICAM1
Entrez
Uniprot