TRIB2 Antibody (8D11)

Images

 
Western Blot: TRIB2 Antibody (8D11) [NBP1-48030] Analysis of extracts (35ug) from 9 different cell lines by using anti-TRIB2 monoclonal antibody.
Immunohistochemistry-Paraffin: TRIB2 Antibody (8D11) [NBP1-48030] - Staining of paraffin-embedded Human endometrium tissue using anti-TRIB2 mouse monoclonal antibody.
Flow Cytometry: TRIB2 Antibody (8D11) [NBP1-48030] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-TRIB2 antibody, and then analyzed ...read more
Western Blot: TRIB2 Antibody (8D11) [NBP1-48030] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TRIB2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates ...read more
Immunohistochemistry-Paraffin: TRIB2 Antibody (8D11) [NBP1-48030] - Staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-TRIB2 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: TRIB2 Antibody (8D11) [NBP1-48030] - Staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-TRIB2 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: TRIB2 Antibody (8D11) [NBP1-48030] - Staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TRIB2 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: TRIB2 Antibody (8D11) [NBP1-48030] - Staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-TRIB2 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: TRIB2 Antibody (8D11) [NBP1-48030] - Staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-TRIB2 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: TRIB2 Antibody (8D11) [NBP1-48030] - Staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-TRIB2 mouse monoclonal antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-P
Clone
8D11
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

TRIB2 Antibody (8D11) Summary

Immunogen
Protein expressed in 293T cell transfected with human TRIB2 expression vector
Specificity
This antibody is specific for Homo sapiens tribbles homolog 2 (Drosophila) (TRIB2), transcript variant 1.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
TRIB2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000-2000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:50
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TRIB2 Antibody (8D11)

  • C5FW
  • FLJ57420
  • GS3955
  • TRB-2
  • TRB2tribbles homolog 2
  • tribbles homolog 2 (Drosophila)

Background

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol TRIB2
Entrez