TRHR Antibody

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Western Blot: TRHR Antibody [NBP1-01042] - Thyrotropin-Releasing Hormone Receptor Antibody Western blot (WB) analysis of TRH-R1 (W234) antibody in extracts from COS7 cells.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-01042
    • Availability
      Product Discontinued

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TRHR Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 250-300 of Human TRH-R1.
Clonality
Polyclonal
Host
Rabbit
Gene
TRHR
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
Application Notes
Western blot (WB) analysis of TRH-R1 (W234) pAb in extracts from COS7 cells.
Theoretical MW
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This antibody is reactive against Human, Mouse, Rat

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TRHR Antibody

  • MGC141920
  • Thyroliberin Receptor
  • thyrotropin-releasing hormone receptor
  • TRHR
  • TRH-R
  • TRHR1

Background

Thyrotrophin-releasing hormone (TRH) is a hypothalamic tripeptide that stimulates, via its receptor in the anterior pituitary gland, the release of thyrotrophin (TSH) and prolactin. The TRH receptors, TRH-R1 and TRH-R2, are G protein-coupled proteins containing seven transmembrane domains and other conserved regions. In rat, two isoforms exist, TRH-R (412) and TRH-R (387), that differ at their carboxy termini. TRH receptors are distributed throughout the central and peripheral nervous systems and are present in a variety of tissues. TRH-R2 displays 50% homology to TRH-R1 and is more restricted to the central nervous system than TRH-R1. Mutation in the TRH receptor gene is associated with isolated central hypothyroidism, a rare disorder characterized by insufficient TSH secretion resulting in low levels of thyroid hormones.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional TRHR Products

Bioinformatics Tool for TRHR Antibody (NBP1-01042)

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Bioinformatics

Gene Symbol TRHR
Entrez