TRANCE/TNFSF11/RANK L Recombinant Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Concentration
Lyoph

Order Details

TRANCE/TNFSF11/RANK L Recombinant Protein Summary

Description
A recombinant protein corresponding to Human TRANCE/TNFSF11/RANK L

Source: E. coli

Amino Acid Sequence: The amino acid sequence of this product is not available.
Preparation
Method
E. coli
Details of Functionality
The EDSO as determined by the dose-dependent stimulation of IL-8 production by human PBMC is <10 ng/ml.
Gene
TNFSF11
Endotoxin Note
<0.1 ng/ug

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
From 5 mM Tris, pH 7.6 + 75 mM NaCl.
Concentration
Lyoph
Reconstitution Instructions
Reconstitute with water to a final concentration of 0.1 - 1.0 mg/ml.

Notes

After reconstituted, dilute further with other aqueous solutions.

Alternate Names for TRANCE/TNFSF11/RANK L Recombinant Protein

  • CD254 antigen
  • CD254
  • ODF
  • OPGL
  • OPGLOPTB2
  • Osteoclast differentiation factor
  • Osteoprotegerin ligand
  • RANK L
  • RANKLreceptor activator of nuclear factor kappa B ligand
  • Receptor activator of nuclear factor kappa-B ligand
  • sOdf
  • TNF-related activation-induced cytokine
  • TNFSF11
  • TRANCE
  • TRANCEODFhRANKL2
  • tumor necrosis factor (ligand) superfamily, member 11
  • tumor necrosis factor ligand superfamily member 11

Background

Human RANK (receptor activator of NF-kB) is a member of the TNFR family, identified as a dentritic cell membrane protein. Human soluble RANK Ligand is a soluble 20.0 kDa polypeptide, comprising the TNF homologous region of RANKL (176 amino acid residues).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Blogs on TRANCE/TNFSF11/RANK L.

The diverse functions of RANKL/TRANCE/TNFSF11
RANKL (also known as TNF-related activation-induced cytokine), or receptor activator of nuclear factor-?B ligand, was first discovered as a key player in the RANKL/RANK/OPG osteoclast formation pathway. Osteoclasts are large multinucleate cells t...  Read full blog post.

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Bioinformatics

Gene Symbol TNFSF11
Entrez
Uniprot

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