TRAIL R4/TNFRSF10D/DcR2 Antibody (DJR4-1)

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-77871
    • Availability
      Product Discontinued

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TRAIL R4/TNFRSF10D/DcR2 Antibody (DJR4-1) Summary

Immunogen
Extracellular domain of DcR2-human IgG1 Fc fusion protein
Specificity
DcR2 (DJR4-1)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF10D
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 1.0 microgram per million cells in 100 microliter volume or 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Positive Control
DCXR Lysate (NBL1-09762)

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.2)
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for TRAIL R4/TNFRSF10D/DcR2 Antibody (DJR4-1)

  • CD264 antigen
  • CD264
  • DcR2
  • DCR2decoy with truncated death domain
  • Decoy receptor 2
  • TNF receptor-related receptor for TRAIL
  • TNF-related apoptosis-inducing ligand receptor 4
  • TNFRSF10D
  • TRAIL R4
  • TRAILR4
  • TRAIL-R4
  • TRAILR4TRAIL receptor 4
  • TRUNDDTRAIL receptor with a truncated death domain
  • tumor necrosis factor receptor superfamily member 10D
  • tumor necrosis factor receptor superfamily, member 10d, decoy with truncateddeath domain

Background

DcR2 (decoy receptor 2), also known as TRAIL-R4, TRUNDD, and CD264, is 386 amino acids in length and a member of the TNF receptor family. Although this receptor binds to the cytotoxic ligand TRAIL, it contains a truncated death domain and functions as an inhibitory receptor. When overexpressed, the DcR2 receptor can protect cells against TRAIL-mediated cytotoxicity. The DcR2 receptor is expressed in a variety of normal human tissues, but is absent in most tumors. Ultraviolet radiation has been shown to upregulate DcR2 expression on human keratinocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TNFRSF10D
Entrez