TRAIL R3/TNFRSF10C Antibody

Images

 
Western Blot: TRAIL R3/TNFRSF10C Antibody [NBP1-77295] - HeLa cell (A), mouse (B) and rat (C) liver tissue lysates with TRAIL-R3 antibody at 1 ug/ml.
Immunofluorescence: TRAIL R3/TNFRSF10C Antibody [NBP1-77295] - Immunofluorescence of DcR1 in rat liver tissue with DcR1 antibody at 10 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

TRAIL R3/TNFRSF10C Antibody Summary

Immunogen
Antibody was raised against a peptide corresponding to amino acids in the extracellular domain of human DcR1 precursor. The immunogen is located within amino acids 90 - 140 of DcR1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TNFRSF10C
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
  • Immunofluorescence 10 ug/ml
Application Notes
DcR1 antibody can be used for detection of DcR1 by Western blot at 0.5 to 1 mg/ml. An approximate 65 kDa band can be detected.
Theoretical MW
65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
TRAIL R3/TNFRSF10C Peptide (NBP1-77295PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TRAIL R3/TNFRSF10C Antibody

  • Antagonist decoy receptor for TRAIL/Apo-2L
  • CD263 antigen
  • CD263
  • cytotoxic TRAIL receptor-3
  • DcR1
  • DCR1MGC149502
  • Decoy receptor 1
  • Decoy TRAIL receptor without death domain
  • LITMGC149501
  • Lymphocyte inhibitor of TRAIL
  • TNFRSF10C
  • TRAIL R3
  • TRAIL receptor 3
  • TRAIL receptor without an intracellular domain
  • TRAILR3
  • TRAIL-R3
  • TRAILR3TNF-related apoptosis-inducing ligand receptor 3
  • TRIDDCR1-TNFR
  • tumor necrosis factor receptor superfamily member 10C
  • tumor necrosis factor receptor superfamily, member 10c, decoy without anintracellular domain

Background

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts are expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB100-56618
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NBP1-76985
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
H00003126-M01
Species: Hu
Applications: WB, ELISA, IHC-P
AF1067
Species: Hu, Mu, Rt
Applications: WB, IHC, Neut
NB100-56116
Species: Hu, Mu, Rt, Ge
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
AF1067
Species: Hu, Mu, Rt
Applications: WB, IHC, Neut
NBP1-77020
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NB100-56505
Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-ready
NB120-13550
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
126-FL/CF
Species: Hu
NB100-56708
Species: Hu, Mu, Rt, Po, ChHa, Ma
Applications: WB, Simple Western, EM, Flow, IB, ICC/IF, IHC, IHC-Fr, IHC-P, CyTOF-ready
NB100-56118
Species: Hu, Mu, Rt, Ca, Ge
Applications: IHC, IHC-Fr, IHC-P, IP, Flow-IC

Publications for TRAIL R3/TNFRSF10C Antibody (NBP1-77295) (0)

There are no publications for TRAIL R3/TNFRSF10C Antibody (NBP1-77295).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for TRAIL R3/TNFRSF10C Antibody (NBP1-77295) (0)

There are no reviews for TRAIL R3/TNFRSF10C Antibody (NBP1-77295). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TRAIL R3/TNFRSF10C Antibody (NBP1-77295) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional TRAIL R3/TNFRSF10C Products

Bioinformatics Tool for TRAIL R3/TNFRSF10C Antibody (NBP1-77295)

Discover related pathways, diseases and genes to TRAIL R3/TNFRSF10C Antibody (NBP1-77295). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TRAIL R3/TNFRSF10C Antibody (NBP1-77295)

Discover more about diseases related to TRAIL R3/TNFRSF10C Antibody (NBP1-77295).
 

Pathways for TRAIL R3/TNFRSF10C Antibody (NBP1-77295)

View related products by pathway.

PTMs for TRAIL R3/TNFRSF10C Antibody (NBP1-77295)

Learn more about PTMs related to TRAIL R3/TNFRSF10C Antibody (NBP1-77295).
 

Research Areas for TRAIL R3/TNFRSF10C Antibody (NBP1-77295)

Find related products by research area.

Blogs on TRAIL R3/TNFRSF10C

There are no specific blogs for TRAIL R3/TNFRSF10C, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our TRAIL R3/TNFRSF10C Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol TNFRSF10C
Entrez
Uniprot