TRAIL R3/TNFRSF10C Antibody (TRAIL-R3-02) [PE] Summary
TRAIL-R3 (aa 1-280) - hIgGhc fusion protein
The TRAIL-R3-02 reacts with TRAIL-R3, a 35 kDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
Protein A purified
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Packaging, Storage & Formulations
Store at 4C in the dark.
PE (A=488, E=575)
PBS and 0.2% (w/v) high grade BSA (protease free)
15mM Sodium Azide
Protein A purified
- Flow Cytometry 1:10-1:1000
Store in the dark. Avoid prolonged exposure to light.
Alternate Names for TRAIL R3/TNFRSF10C Antibody (TRAIL-R3-02) [PE]
- Antagonist decoy receptor for TRAIL/Apo-2L
- CD263 antigen
- cytotoxic TRAIL receptor-3
- Decoy receptor 1
- Decoy TRAIL receptor without death domain
- Lymphocyte inhibitor of TRAIL
- TRAIL receptor 3
- TRAIL receptor without an intracellular domain
- TRAILR3TNF-related apoptosis-inducing ligand receptor 3
- tumor necrosis factor receptor superfamily member 10C
- tumor necrosis factor receptor superfamily, member 10c, decoy without anintracellular domain
The DJR3 monoclonal antibody reacts with human Decoy receptor 1 (DcR1), a glycophospholipid-anchored cell surface protein also known as TRAIL-R3, TRID, and LIT. DcR1 has an extracellular TRAIL binding domain and lacks the cytoplasmic death domain (DD) shared by several members of the TNF receptor superfamily. DcR1, along with DcR2, protects cells from TRAIL-mediated cytotoxicity. DcR1 binds to TRAIL and inhibits binding of TRAIL to DR4 or DR5. DcR1 is expressed broadly in many normal tissues at low level, but not in most tumors. Overexpression of DcR1 attenuates TRAIL-induced apoptosis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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