TRAIL R2/TNFRSF10B Antibody (MD5-1) [Biotin]

Images

 
Flow Cytometry: TRAIL R2/TNFRSF10B Antibody (MD5-1) [Biotin] [NBP1-43530] - Staining of non-transfected (left) and mouse DR5 transfected (right) BHK cells with 0.06 ug of Golden Syrian Hamster IgG Isotype Control Biotin ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
MD5-1
Clonality
Monoclonal
Host
Armenian Hamster
Concentration
0.5 mg/ml

Order Details

Available Conjugates

TRAIL R2/TNFRSF10B Antibody (MD5-1) [Biotin] Summary

Immunogen
The immunogen for this antibody was DR5.
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
TNFRSF10B
Purity
Protein A or G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Conjugate
Biotin
Format
Biotin (A=N/A, E=N/A)
Buffer
Aqueous buffer, may contain carrier protein/stabilizer (proprietary)
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
The MD5-1 antibody has been tested by flow cytometric analysis of mouse DR5-transfected cells. This can be used at less than or equal to 0.25 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.
Readout System

Alternate Names for TRAIL R2/TNFRSF10B Antibody (MD5-1) [Biotin]

  • CD262 antigen
  • CD262
  • death domain containing receptor for TRAIL/Apo-2L
  • Death receptor 5
  • DR5
  • DR5TRICK2B
  • Fas-like protein
  • KILLER/DR5
  • KILLERapoptosis inducing protein TRICK2A/2B
  • TNF-related apoptosis-inducing ligand receptor 2
  • TNFRSF10B
  • TRAIL R2/TNFRSF10B
  • TRAIL receptor 2
  • TRAILR2
  • TRAIL-R2apoptosis inducing receptor TRAIL-R2
  • TRAILR2cytotoxic TRAIL receptor-2
  • TRICK2
  • TRICK2A
  • TRICKB
  • tumor necrosis factor receptor superfamily member 10B
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor-like protein ZTNFR9
  • ZTNFR9

Background

The MD5-1 monoclonal antibody reacts with mouse DR5, also known as TRAIL-R2, Apo2, TRICK2, and KILLER. DR5 binds to TRAIL, activates NF-kappaB, and induces TRAIL-mediated apoptosis. DR5 mRNA is expressed broadly by normal tissue and human antigen is also expressed by some tumor cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol TNFRSF10B
Entrez
Uniprot

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