TRAIL R2/TNFRSF10B Antibody (DR5-01-1) [FITC]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
DR5-01-1
Clonality
Monoclonal
Host
Mouse
Concentration
0.1 mg/ml

TRAIL R2/TNFRSF10B Antibody (DR5-01-1) [FITC] Summary

Immunogen
Recombinant fusion protein of human IgG heavy chain and extracellular domain of DR5 (NM_003842.4).
Specificity
The antibody DR5-01-1 recognizes an extracellular domain of TRAIL-R2 (DR5). TRAIL-R2 is one of two TNF superfamily member intracellular death domain containing receptors for TRAIL (APO2L).
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF10B
Purity
Protein A purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Conjugate
FITC
Format
FITC (A=495, E=519)
Buffer
PBS and 0.2% (w/v) high grade BSA (protease free)
Preservative
15mM Sodium Azide
Concentration
0.1 mg/ml
Purity
Protein A purified

Applications/Dilutions

Dilutions
  • Flow Cytometry 1-10 ug/ml
Publications
Read Publication using NBP1-45022.

Notes

Store in the dark. Avoid prolonged exposure to light.

Alternate Names for TRAIL R2/TNFRSF10B Antibody (DR5-01-1) [FITC]

  • CD262 antigen
  • CD262
  • death domain containing receptor for TRAIL/Apo-2L
  • Death receptor 5
  • DR5
  • DR5TRICK2B
  • Fas-like protein
  • KILLER/DR5
  • KILLERapoptosis inducing protein TRICK2A/2B
  • TNF-related apoptosis-inducing ligand receptor 2
  • TNFRSF10B
  • TRAIL R2/TNFRSF10B
  • TRAIL receptor 2
  • TRAILR2
  • TRAIL-R2apoptosis inducing receptor TRAIL-R2
  • TRAILR2cytotoxic TRAIL receptor-2
  • TRICK2
  • TRICK2A
  • TRICKB
  • tumor necrosis factor receptor superfamily member 10B
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor-like protein ZTNFR9
  • ZTNFR9

Background

The MD5-1 monoclonal antibody reacts with mouse DR5, also known as TRAIL-R2, Apo2, TRICK2, and KILLER. DR5 binds to TRAIL, activates NF-kappaB, and induces TRAIL-mediated apoptosis. DR5 mRNA is expressed broadly by normal tissue and human antigen is also expressed by some tumor cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TRAIL R2/TNFRSF10B Antibody (NBP1-45022)(1)

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

PE Labeled NBP1-45023

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol TNFRSF10B
Entrez
Uniprot

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