TRAIL R2/TNFRSF10B Antibody (DJR2-4)

Images

 
Flow Cytometry: TRAIL R2/TNFRSF10B Antibody (DJR2-4) [NBP1-43136] - Analysis using the PE conjugate of NBP1-43136. Detection of human MOLT-4 cell line and human DR5-transfected cells using TRAIL-R2 PE. This can be used ...read more
Flow Cytometry: TRAIL R2/TNFRSF10B Antibody (DJR2-4) [NBP1-43136] - Staining of human DR5-transfected cells with 0.5 ug of Mouse IgG1 K Isotype Control Purified (open histogram) or 0.5 ug of Anti-Human CD262 (DR5) ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-43136
    • Availability
      Product Discontinued

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TRAIL R2/TNFRSF10B Antibody (DJR2-4) Summary

Immunogen
The immunogen for this antibody was DR5.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF10B
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
The DJR2-4 antibody has been tested by flow cytometric analysis of human MOLT-4 cell line and human DR5-transfected cells. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous, may contain carrier protein/stabilizer.
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for TRAIL R2/TNFRSF10B Antibody (DJR2-4)

  • CD262 antigen
  • CD262
  • death domain containing receptor for TRAIL/Apo-2L
  • Death receptor 5
  • DR5
  • DR5TRICK2B
  • Fas-like protein
  • KILLER/DR5
  • KILLERapoptosis inducing protein TRICK2A/2B
  • TNF-related apoptosis-inducing ligand receptor 2
  • TNFRSF10B
  • TRAIL R2
  • TRAIL receptor 2
  • TRAILR2
  • TRAIL-R2apoptosis inducing receptor TRAIL-R2
  • TRAILR2cytotoxic TRAIL receptor-2
  • TRICK2
  • TRICK2A
  • TRICKB
  • tumor necrosis factor receptor superfamily member 10B
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor-like protein ZTNFR9
  • ZTNFR9

Background

The DJR2-4 monoclonal antibody reacts with human DR5, also known as TRAIL-R2, Apo2, TRICK2 and KILLER. DR5 binds to TRAIL, activates NF-kappaB, and induces TRAIL-mediated apoptosis. DR5 is expressed broadly by normal tissues as well as several tumor cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Diseases for TRAIL R2/TNFRSF10B Antibody (NBP1-43136)

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Bioinformatics

Gene Symbol TNFRSF10B
Entrez