TRAIL R1/TNFRSF10A Antibody (DJR1)

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Flow Cytometry: TRAIL R1/TNFRSF10A Antibody (DJR1) [NB100-77848] - Analysis using the Biotin conjugate of NB100-77848. Staining of human DR4 transfected cells with Anti-Human CD261 (DR4) Biotin Streptavidin PE. ...read more
Flow Cytometry: TRAIL R1/TNFRSF10A Antibody (DJR1) [NB100-77848] - man DR4 transfected cells stained with purified DJR1, followed by anti-mouse IgG FITC

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-77848
    • Availability
      Product Discontinued

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TRAIL R1/TNFRSF10A Antibody (DJR1) Summary

Immunogen
Extracellular domain of DR4-human IgG1 Fc fusion protein
Specificity
DR4 (DJR1)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF10A
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per one millioncells in 100 microliter volume. It is recommended that the reagent be titrated for optimal performance for each application.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.2)
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for TRAIL R1/TNFRSF10A Antibody (DJR1)

  • APO2
  • CD261 antigen
  • CD261
  • cytotoxic TRAIL receptor
  • Death receptor 4
  • DR4 TRAIL receptor 1
  • DR4
  • TNF-related apoptosis inducing ligand receptor 1
  • TNF-related apoptosis-inducing ligand receptor 1
  • TNFRSF10A
  • TRAIL R1
  • TRAILR1
  • TRAIL-R1
  • TRAILR-1
  • TRAILR1MGC9365
  • tumor necrosis factor receptor superfamily member 10A
  • tumor necrosis factor receptor superfamily, member 10a

Background

DR4 is 56 kD member 10A of the TNFR superfamily (TNFRSF10A), also known as TRAIL-R1, Apo-2, and CD261. It is expressed at low levels by activated T cells and some tumors. After TRAIL engagement, DR4 (TRAIL-R1), through activation of NF- kappaB, induces apoptosis in the TRAIL ligated cell.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Additional TRAIL R1/TNFRSF10A Products

Bioinformatics Tool for TRAIL R1/TNFRSF10A Antibody (NB100-77848)

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Diseases for TRAIL R1/TNFRSF10A Antibody (NB100-77848)

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PTMs for TRAIL R1/TNFRSF10A Antibody (NB100-77848)

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Bioinformatics

Gene Symbol TNFRSF10A
Entrez