TRAIL R1/TNFRSF10A Antibody (32A1380)


Western Blot: TRAIL R1/TNFRSF10A Antibody (32A1380) [NB100-56747] - Analysis of DR4 in Daudi cell lysate using DR4 antibody at 2 ug/ml. Goat anti-mouse Ig HRP secondary antibody and PicoTect ECL substrate solution were more
Simple Western: TRAIL R1/TNFRSF10A Antibody (32A1380) [NB100-56747] - Simple Western lane view shows a specific band for TRAIL R1 in 0.5 mg/ml of Daudi lysate. This experiment was performed under reducing conditions more

Product Details

Reactivity HuSpecies Glossary
Applications WB, Simple Western, Flow, ICC/IF
1.0 mg/ml

TRAIL R1/TNFRSF10A Antibody (32A1380) Summary

This monoclonal antibody was raised against a peptide corresponding to amino acid 2 to 21 of human DR4.
IgG1 Kappa
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.05% Sodium Azide
1.0 mg/ml
Protein G purified


  • Western Blot 2-4 ug/ml
  • Simple Western 20 ug/ml
  • Flow Cytometry 1:20-1:2000
  • Immunocytochemistry/Immunofluorescence
Application Notes
A 57 kDa band should be observed. This antibody is routinely tested be western blot analysis. For other applicatons, please refer to appropriate published references for more information.In Simple Western only 10-15 uL of the recommended dilution is used per data point. Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 26044191)
Read Publications using
NB100-56747 in the following applications:

Reactivity Notes


Alternate Names for TRAIL R1/TNFRSF10A Antibody (32A1380)

  • APO2
  • CD261 antigen
  • CD261
  • cytotoxic TRAIL receptor
  • Death receptor 4
  • DR4 TRAIL receptor 1
  • DR4
  • TNF-related apoptosis inducing ligand receptor 1
  • TNF-related apoptosis-inducing ligand receptor 1
  • TRAIL-R1
  • TRAILR-1
  • TRAILR1MGC9365
  • tumor necrosis factor receptor superfamily member 10A
  • tumor necrosis factor receptor superfamily, member 10a


Cells undergo programmed cell death (Apoptosis) in response to various stimuli. Apoptosis is essential for morphogenesis, tissue homeostasis, and host defense Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4). The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kB activation in many tissues and cells.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: WB, Flow, ICC/IF, IHC-P
Species: Hu, Mu, Rt, Ge
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Species: Hu
Applications: WB, IHC, Neut
Species: Hu
Applications: WB, IHC, IHC-Fr, IHC-P, IP
Species: Hu
Applications: WB, ELISA
Species: Hu, Mu, Rt, Po, ChHa, Ma
Applications: WB, Simple Western, EM, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
Species: Hu
Applications: WB, ICC/IF
Species: Hu
Applications: WB, ELISA, IHC, IHC-P, S-ELISA
Species: Hu, Mu
Applications: WB, Simple Western, IP
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, Flow, IHC-P
Species: Hu, Mu, Rt, Ca, Ge
Applications: IHC, IHC-Fr, IHC-P, IP, Flow-IC
Species: Hu, Mu, Ca
Applications: WB, IHC, IHC-P, IP
Supplier Logo

Publications for TRAIL R1/TNFRSF10A Antibody (NB100-56747)(20)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 5 applications: Flow, Flow - CS, Flow-IC, ICC/IF, WB.

Filter By Application
Flow - CS
All Applications
Filter By Species
All Species
Showing Publications 1 - 10 of 20. Show All 20 Publications.
Publications using NB100-56747 Applications Species
Foster KA, Jane EP, Premkumar DR et al. NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5 Int. J. Oncol. 2015 Jun 05 [PMID:26044191] (ICC/IF, Human) ICC/IF Human
Qiu F, Hu M, Tang B, Liu X et al. Annexin V-TRAIL fusion protein is a more sensitive and potent apoptotic inducer for cancer therapy. Sci Rep 2013 Dec 20 [PMID:24356445] (WB, Human) WB Human
Abdulghani Junaid, Allen Joshua E, Dicker David T et al. Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis. PLoS One. 2013 [PMID:24086526] (Human) Human
Park S, Cho DH, Andera L et al. Curcumin enhances TRAIL-induced apoptosis of breast cancer cells by regulating apoptosis-related proteins. Mol Cell Biochem 2013 Nov [PMID:23846485] (WB, Human) WB Human
Allen JE, Ferrini R, Dicker DT et al. Targeting TRAIL death receptor 4 with trivalent DR4 Atrimer complexes. Mol Cancer Ther. 2012 Oct [PMID:22802267]
Jane EP, Premkumar DR, Pollack IF. Bortezomib sensitizes malignant human glioma cells to TRAIL, mediated by inhibition of the NF-{kappa}B signaling pathway. Mol Cancer Ther. 2011 Jan [PMID:21220502] (WB) WB
Lin YD, Chen S, Yue P et al. CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells. Cancer Res. 2008 Jul 1 [PMID:18593935] (WB) WB
Le Poole IC, ElMasri WM, Denman CJ et al. Langerhans cells and dendritic cells are cytotoxic towards HPV16 E6 and E7 expressing target cells. Cancer Immunol Immunother. 2008 Jun [PMID:18004565] (Flow - CS, Human) Flow - CS Human
Tsurushima H, Yuan X, Dillehay LE, Leong KW. Radioresponsive tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene therapy for malignant brain tumors. Cancer Gene Ther. 2007 Aug [PMID:17541421] (Flow-IC, Human) Flow-IC Human
Lee SH, Kim YK, Kim CS et al. E2 of hepatitis C virus inhibits apoptosis. J Immunol. 2005 Dec 15 [PMID:16339562]
Show All 20 Publications.

Reviews for TRAIL R1/TNFRSF10A Antibody (NB100-56747) (0)

There are no reviews for TRAIL R1/TNFRSF10A Antibody (NB100-56747). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TRAIL R1/TNFRSF10A Antibody (NB100-56747) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NBP2-27350APC
DyLight 350 Labeled NBP2-27350UV
DyLight 405 Labeled NBP2-27350V
DyLight 405LS Labeled NBP2-27350V3
DyLight 488 Labeled NBP2-27350G
DyLight 550 Labeled NBP2-27350R
DyLight 650 Labeled NBP2-27350C
DyLight 680 Labeled NBP2-27350FR
DyLight 755 Labeled NBP2-27350IR
HRP Labeled NBP2-27350H
PE Labeled NBP2-27350PE
PerCP Labeled NBP2-27350PCP

Additional TRAIL R1/TNFRSF10A Antibody (32A1380) Products

Related Products by Gene

Bioinformatics Tool for TRAIL R1/TNFRSF10A Antibody (NB100-56747)

Discover related pathways, diseases and genes to TRAIL R1/TNFRSF10A Antibody (NB100-56747). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TRAIL R1/TNFRSF10A Antibody (NB100-56747)

Discover more about diseases related to TRAIL R1/TNFRSF10A Antibody (NB100-56747).

Pathways for TRAIL R1/TNFRSF10A Antibody (NB100-56747)

View related products by pathway.

PTMs for TRAIL R1/TNFRSF10A Antibody (NB100-56747)

Learn more about PTMs related to TRAIL R1/TNFRSF10A Antibody (NB100-56747).

Research Areas for TRAIL R1/TNFRSF10A Antibody (NB100-56747)

Find related products by research area.


There are no specific blogs for TRAIL R1/TNFRSF10A, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol TNFRSF10A

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NB100-56747 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought