TRAF-4 Antibody

Images

 
Western Blot: TRAF-4 Antibody [NBP1-47305] - Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-TRAF-4 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml
 

Independent Antibodies

 

Biological Strategies

     

Order Details

TRAF-4 Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 225 and 275 of human TNF Receptor-Associated Factor 4 using the numbering given in entry NP_004286.2 (GeneID 9618).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRAF4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 ug/mg lysate

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TRAF-4 Antibody

  • CART1
  • CART1RING finger protein 83
  • Cysteine-rich domain associated with RING and Traf domains protein 1
  • Metastatic lymph node gene 62 protein
  • MLN 62
  • MLN62
  • MLN62cysteine-rich domain associated with ring and TRAF domain
  • RNF83malignant 62
  • TNF receptor-associated factor 4
  • TRAF4
  • TRAF-4
  • tumor necrosis receptor-associated factor 4A

Background

This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TRAF4
Entrez