TRAF-2 Antibody



Product Details

Product Discontinued
View other related TRAF-2 Primary Antibodies

Order Details

    • Catalog Number
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

TRAF-2 Antibody Summary

This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region human TRAF2.
The product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is predicted to react with TRAF2 from human and mouse sources based on a 100% identity with the immunizing sequence. Reactivity with TRAF2 from other sources has not been determined.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Sodium Phosphate (pH 7.2) and 0.15M NaCl
0.01% Sodium Azide
LYOPH mg/ml
Immunogen affinity purified
Reconstitution Instructions
Reconstitute with 50 ul of distilled water to a final concentration of 1.0 mg/ml.

Reactivity Notes

Human, mouse


TRAF2, or Tumor Necrosis factor (TNF) Receptor-Associated Factor 2, is an adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Association to the receptor is also mediated by the interaction with TRADD. TRAF2 mediates activation of NF-kappa-B and MAPK8/JNK and is involved in apoptosis. TRAF2 forms a heterodimeric complex with TRAF1, which then recruits the inhibitor-of-apoptosis proteins (IAPs), apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2 for the inhibition of caspase activation. In this way it functions as a mediator of the anti-apoptotic signals from TNF receptors. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. TRAF2 may be involved in IL-15 signaling. Multiple alternatively spliced transcript variants exist, but the biological validity of only one transcript has been determined.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
Applications: Func-Inh
Species: Hu, Mu, Rt
Applications: WB, Flow, IHC, IHC-P, Flow-CS
Species: Hu, Bv, Ca
Applications: WB, IHC, IHC-P, IP
Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Species: Hu, Mu, Rt
Applications: B/N, In vitro
Species: Hu, Mu
Applications: WB, IHC-P
Species: Hu, Mu, Rt
Applications: WB
Species: Hu
Applications: Flow, Neut
Species: Hu, Rt
Applications: IHC, ICC, ICFlow
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, AgAct
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, S-ELISA
Species: Hu
Applications: WB, Simple Western, ICC
Species: Hu, Rt, Ca, Mk
Applications: WB, IHC, IHC-P, IP
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF

Publications for TRAF-2 Antibody (NBP1-42777) (0)

There are no publications for TRAF-2 Antibody (NBP1-42777).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for TRAF-2 Antibody (NBP1-42777) (0)

There are no reviews for TRAF-2 Antibody (NBP1-42777). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

FAQs for TRAF-2 Antibody (NBP1-42777) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional TRAF-2 Antibody Products

Related Products by Gene

Bioinformatics Tool for TRAF-2 Antibody (NBP1-42777)

Discover related pathways, diseases and genes to TRAF-2 Antibody (NBP1-42777). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TRAF-2 Antibody (NBP1-42777)

Discover more about diseases related to TRAF-2 Antibody (NBP1-42777).

Pathways for TRAF-2 Antibody (NBP1-42777)

View related products by pathway.

PTMs for TRAF-2 Antibody (NBP1-42777)

Learn more about PTMs related to TRAF-2 Antibody (NBP1-42777).

Blogs on TRAF-2

There are no specific blogs for TRAF-2, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol TRAF2

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-42777 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.