TRAF-2 Antibody (4C11)

Images

 
Western Blot: TRAF-2 Antibody (4C11) [H00007186-M04] - Analysis of TRAF2 expression in transfected 293T cell line by TRAF2 monoclonal antibody (M04), clone 4C11. Lane 1: TRAF2 transfected lysatE (55.9 KDa). Lane 2: ...read more
Proximity Ligation Assay: TRAF-2 Antibody (4C11) [H00007186-M04] - Analysis of protein-protein interactions between IKBKB and TRAF2. HeLa cells were stained with anti-IKBKB rabbit purified polyclonal 1:1200 and ...read more

Product Details

Summary
Product Discontinued
View other related TRAF-2 Primary Antibodies

Order Details


    • Catalog Number
      H00007186-M04
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

TRAF-2 Antibody (4C11) Summary

Immunogen
TRAF2 (AAH43492, 1 a.a. - 501 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
Specificity
TRAF2 - TNF receptor-associated factor 2 (4C11)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TRAF2
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Proximity Ligation Assay
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TRAF-2 Antibody (4C11)

  • E3 ubiquitin-protein ligase TRAF2
  • EC 6.3.2.-
  • MGC:45012
  • TNF receptor-associated factor 2
  • TRAF2
  • TRAF-2
  • TRAP3
  • TRAP3TRAP
  • tumor necrosis factor type 2 receptor associated protein 3
  • Tumor necrosis factor type 2 receptor-associated protein 3

Background

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-29323
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
NB100-56508
Species: Hu, Mu, Rt
Applications: WB, Flow, IHC, IHC-P, CyTOF-ready, Flow-CS
NB100-56170
Species: Hu, Bv, Ca
Applications: WB, IHC, IHC-P, IP
NB100-56505
Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-ready
NBP2-26506
Species: Hu, Mu, Rt
NB100-56654
Species: Hu, Mu
Applications: WB, IHC-P
MAB17761
Species: Hu, Mu, Rt
Applications: WB, ICC
MAB1419
Species: Hu, Rt
Applications: IHC, CyTOF-ready, ICC, ICFlow
NBP1-77077
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
DDX0131P-100
Species: Hu
Applications: Flow, Func, ICC/IF, IHC, IHC-Fr, IHC-P
H00001513-M01
Species: Hu
Applications: WB, ELISA, IHC-P
NBP2-37576
Species: Hu, Mu, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC
NB100-317
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
H00007186-M04
Species: Hu
Applications: WB, ELISA, PLA

Publications for TRAF-2 Antibody (H00007186-M04) (0)

There are no publications for TRAF-2 Antibody (H00007186-M04).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for TRAF-2 Antibody (H00007186-M04) (0)

There are no reviews for TRAF-2 Antibody (H00007186-M04). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for TRAF-2 Antibody (H00007186-M04) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional TRAF-2 Products

Bioinformatics Tool for TRAF-2 Antibody (H00007186-M04)

Discover related pathways, diseases and genes to TRAF-2 Antibody (H00007186-M04). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TRAF-2 Antibody (H00007186-M04)

Discover more about diseases related to TRAF-2 Antibody (H00007186-M04).
 

Pathways for TRAF-2 Antibody (H00007186-M04)

View related products by pathway.

PTMs for TRAF-2 Antibody (H00007186-M04)

Learn more about PTMs related to TRAF-2 Antibody (H00007186-M04).
 

Research Areas for TRAF-2 Antibody (H00007186-M04)

Find related products by research area.

Blogs on TRAF-2

There are no specific blogs for TRAF-2, but you can read our latest blog posts.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our TRAF-2 Antibody (4C11) and receive a gift card or discount.

Bioinformatics

Gene Symbol TRAF2
Entrez
Uniprot