TRADD Antibody

Product Discontinued

TRADD Antibody Summary

• Immunogen: Synthetic peptide surrounding amino acid 300 of human TRADD.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TRADD
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 0.5% BSA and 30% Glycerol
• Preservative: 0.01% Thimerosal
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for TRADD Antibody

• MGC11078
• TNFRSF1A-associated via death domainTNFR1-associated DEATH domain protein
• TRADD
• tumor necrosis factor receptor type 1 associated death domain protein
• tumor necrosis factor receptor type 1-associated DEATH domain protein
• tumor necrosis factor receptor-1-associated protein

Background

The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: TRADD
• Entrez:
  • 8717(Human)
• Uniprot:
  • Q15628()