TRADD Antibody

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-63244
    • Availability
      Product Discontinued

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TRADD Antibody Summary

Immunogen
Peptide sequence C-AAGQNGHEEWVG corresponding to the N-terminus of TRADD (NP_700474).
Specificity
NB100-63244 recognizes tumour necrosis factor receptor 1-associated death domain protein (TRADD) isoform 2, a 28kDa death domain containing protein. TRADD is expressed in most tissues. It mediates programmed cell death signalling and NF-kappa beta activation through interaction with tumour necrosis factor receptor superfamily, member 1A. By binding the adaptor protein TRAF2, TRADD reduces the recruitment of inhibitor-of-apoptosis proteins, inhibiting TRAF2 mediated apoptosis. TRADD is also involved in the Fas-induced cell death pathway via its interaction with tumour necrosis factor receptor superfamily, member-6/FAS and adaptor protein FADD/MORT1.
Clonality
Polyclonal
Host
Goat
Gene
TRADD
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
Positive Control
TRADD Lysate (NBL1-17238)

Reactivity Notes

Human. Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
TBS (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TRADD Antibody

  • MGC11078
  • TNFRSF1A-associated via death domainTNFR1-associated DEATH domain protein
  • TRADD
  • tumor necrosis factor receptor type 1 associated death domain protein
  • tumor necrosis factor receptor type 1-associated DEATH domain protein
  • tumor necrosis factor receptor-1-associated protein

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional TRADD Products

Bioinformatics Tool for TRADD Antibody (NB100-63244)

Discover related pathways, diseases and genes to TRADD Antibody (NB100-63244). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for TRADD Antibody (NB100-63244)

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Pathways for TRADD Antibody (NB100-63244)

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PTMs for TRADD Antibody (NB100-63244)

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Research Areas for TRADD Antibody (NB100-63244)

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Blogs on TRADD.

Caspase 9: The Suicidal Cell Whisperer
Cell death via apoptosis is a key cellular function triggered by the cell death receptor family and their ligands which signal through downstream adaptor molecules and the caspase protease family. Among the subclass of initiator caspases that include...  Read full blog post.

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Bioinformatics

Gene Symbol TRADD
Entrez
Uniprot