TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody

Images

 
Western Blot: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [H00007067-D01P] - Analysis of THRA expression in HepG2.
Western Blot: TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody [H00007067-D01P] - Analysis of THRA expression in transfected 293T cell line by THRA polyclonal antibody.Lane 1: THRA transfected lysate(46.80 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody Summary

Immunogen
THRA (NP_955366.1, 1 a.a. - 410 a.a.) full-length human protein. MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFEDQEV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
THRA
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
It has been used for WB.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TR alpha/NR1A1/Thyroid Hormone Receptor alpha Antibody

  • AR7
  • c-ERBA-1
  • c-erbA-alpha
  • EAR7
  • EAR-7
  • EAR-7.1/EAR-7.2
  • ERBA
  • ERBA1thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v-erb-a)oncogene homolog)
  • ERBA-related 7
  • MGC000261
  • MGC43240
  • NR1A 1
  • NR1A1
  • NR1A1THRA3
  • Nuclear receptor subfamily 1 group A member 1
  • THRA
  • THRA1ERB-T-1
  • THRA2
  • thyroid hormone receptor alpha
  • thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a)oncogene homolog, avian)
  • TR alpha
  • triiodothyronine receptor
  • v-ErbA1
  • V-erbA-related protein 7

Background

Thyroid hormone receptors (TR) are ligand dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences called hormone response elements following activation by the appropriate hormone. Thyroid hormones, through their interaction with TR, effect metabolic processes, growth and development in many tissues by regulating the expression of genes for growth hormone, malic enzyme and several hepatic proteins. There are two forms of TR; TR alpha (on chromosome 17) and TR beta (on chromosome 3). Each of these isoforms also has two isoforms; TR alpha 1 and TR alpha 2, and TR beta 1 and TR beta 2 respectively. TR alpha 1 and 2 are identical through amino acid 370, where their sequences diverge. TR alpha 2, which does not bind T3 and is a strong negative regulator of the functional TR, is 80 amino acids longer than TR alpha 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol THRA
Entrez
Uniprot