TORC1 Antibody

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Western Blot: TORC1 Antibody [NBP1-77941] - Antibody shows detection (arrowhead) of secreted MAGP-2 (lane 2) and MAGP-2 present in a MAGP-2 transfected HEK293 lysate (lane 3). No staining is detected in supernatants ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-77941
    • Availability
      Product Discontinued

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TORC1 Antibody Summary

Immunogen
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminal end of human MAGP-2 protein.
Specificity
This antibody is directed against human MAGP-2 protein. A BLAST analysis was used to suggest cross reactivity with MAGP-2 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
CRTC1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:250-1:1000
  • ELISA 1:5000-1:20000
Application Notes
This affinity-purified antibody has been tested for use in ELISA and western blot. Expect a band approximately 20-30 kDa in size corresponding - MAGP-2 protein by western blotting in the appropriate cell lysate or extract.

Reactivity Notes

Reactive in human, chimpanzee

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative
0.01% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TORC1 Antibody

  • CREB regulated transcription coactivator 1
  • CRTC1
  • FLJ14027WAMTP1
  • KIAA0616Transducer of regulated cAMP response element-binding protein 1
  • MECT1
  • MECT1CREB-regulated transcription coactivator 1
  • mucoepidermoid carcinoma translocated 1
  • Mucoepidermoid carcinoma translocated protein 1
  • TORC1
  • TORC1TORC-1
  • Transducer of CREB protein 1
  • transducer of regulated cAMP response element-binding protein (CREB) 1
  • WAMTP1

Background

MAGP-2 (also known as Microfibril-associated glycoprotein 2, MFAP-2, MP25 and Microfibrillar-associated protein 5 precursor) is a secreted, extracellular matrix protein which is a component of the elastin-associated microfibrils. It forms intermolecular disulfide bonds either with other MAGP-2 molecules or with other components of the microfibrils. MAGP-2 is upregulated in some ovarian cancers and is associated with poor survival of ovarian cancer patients.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CRTC1
Entrez