TMPRSS2 Antibody

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Western Blot: TMPRSS2 Antibody [NBP1-20984] - Western blot analysis of TMPRSS2 in Human Pancreas Lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour detected by chemiluminescence using NBP1-20984 at ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

TMPRSS2 Antibody Summary

Immunogen
Peptide with sequence C-TDWIYRQMRADG corresponding to internal region according to NP_005647.2.
Epitope
C terminus
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
TMPRSS2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 - 0.3 ug/ml
  • Peptide ELISA Detection limit 1:8000
Application Notes
WB: Approx. 55 kDa band observed in human pancreas lysates (calculated MW of 53.9 kDa band according to NP_005647.2).
Publications
Read Publication using NBP1-20984.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TMPRSS2 Antibody

  • EC 3.4.21
  • EC 3.4.21.109
  • Epitheliasin
  • FLJ41954
  • PP9284
  • PRSS10
  • PRSS10epitheliasin
  • Serine protease 10
  • TMPRSS2
  • transmembrane protease serine 2
  • transmembrane protease, serine 2
  • transmembrane protease, serine 2, EC 3.4.2110EC 3.4.21.-

Background

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TMPRSS2 Antibody (NBP1-20984)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics Tool for TMPRSS2 Antibody (NBP1-20984)

Discover related pathways, diseases and genes to TMPRSS2 Antibody (NBP1-20984). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on TMPRSS2.

Blocking SARS-CoV-2 Cell Entry: A potential Strategy Against COVID-19 Pandemic
By Jamshed Arslan, Pharm. D., PhD. Coronaviruses are a family of enveloped RNA viruses. Some family members circulate in human populations, but others like severe acute respiratory syndrome coronavirus (SARS-CoV) ar...  Read full blog post.

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Bioinformatics

Gene Symbol TMPRSS2
Entrez
Uniprot
COVID-19 update