TLR8 Antibody (44B05)

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Western Blot: TLR8 Antibody (44B05) [NBP1-45901] - Analysis of TLR8 in cell lysate of 293 transfected with human TLR8.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow
Clone
44B05
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

TLR8 Antibody (44B05) Summary

Immunogen
Recombinant human TLR8.
Isotype
IgG1
Clonality
Monoclonal
Host
Rabbit
Gene
TLR8
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Flow Cytometry
Application Notes
Western blotting (1:200-1000 dilutions) and FACS analysis. Ramos cell lysate can be used as a positive control and a 120 kDa band is detected in Western blotting. For FACS analysis, we recommend 1-4 ml per million cells. However, the optimal conditions should be determined individually.
Agonist

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2), 1.0% BSA and 50% Glycerol
Preservative
0.02% Thimerosal
Purity
Protein G purified

Alternate Names for TLR8 Antibody (44B05)

  • CD288 antigen
  • CD288
  • MGC119599
  • MGC119600
  • TLR8
  • toll-like receptor 8

Background

The TLR8 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TLR8
Entrez
Uniprot