TLR3 Antibody (T3.7C3)



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TLR3 Antibody (T3.7C3) Summary

The immunogen for this antibody was Tolllike receptor 3.
Protein A or G purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Aqueous buffer, may contain carrier protein/stabilizer (proprietary).
0.09% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Protein A or G purified


Application Notes
The T3.7C3 antibody has been tested by immunoblotting of mTLR3 transfected cell lysate and can be used at 1-3ug/ml.

Reactivity Notes

This antibody is reactive to Mouse.


The T3.7C3 antibody reacts with mouse TLR3 and was generated using the sequence of extracellular domain of mouse TLR3. To date, at least twelve members of the Toll family have been identified. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. In the innate immunity system, TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune responses. TLR3 recognizes double-stranded (ds)RNA and induces the activation of NF-kappaB, through MyD88-dependent and -independent pathways and the production of type I interferons (IFNs). Immunoblotting with this antibody gives a MW of ~120 kDa in mTLR3 transfected cells.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Gene Symbol TLR3

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