TLR2 Antibody

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Immunohistochemistry: TLR2 Antibody [NB120-1655] - Immunohistochemical staining of TLR2 on human spleen using NB120-1655.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB120-1655
    • Availability
      Product Discontinued

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TLR2 Antibody Summary

Immunogen
Synthetic peptide: CLEIDASDLQSYEPKSLKSIQNVSHLI, corresponding to amino acids 179-204 of Human TLR2.
Localization
Type I membrane protein
Specificity
Peptide sequence is < 50 % identical to other human TLR receptors in this region.
Clonality
Polyclonal
Host
Goat
Gene
TLR2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:37500
  • Immunohistochemistry 1:125
  • Immunohistochemistry-Paraffin 1:10-1:500
Agonist
Antagonist
Positive Control
TLR2 Lysate (NBL1-16952)

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 1.0 mg/ml BSA
Preservative
0.1% Sodium Azide
Concentration
2.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TLR2 Antibody

  • CD282 antigen
  • CD282
  • TIL4CD282
  • TLR2
  • toll/interleukin 1 receptor-like 4
  • Toll/interleukin-1 receptor-like protein 4
  • toll-like receptor 2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB120-1655
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Applications: ELISA, IHC, IHC-P

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Product General Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional TLR2 Products

Bioinformatics Tool for TLR2 Antibody (NB120-1655)

Discover related pathways, diseases and genes to TLR2 Antibody (NB120-1655). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Research Areas for TLR2 Antibody (NB120-1655)

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Blogs on TLR2.

The role of STING/TMEM173 in gamma and encephalitis Herpes Simplex Virus (HSV)
Stimulator of interferon genes (STING), also known as TMEM173, promotes the production of the interferon’s IFN-alpha and IFN-beta.  STING possesses three functional domains: a cytoplasmic C-terminal tail, a central globular domain, and four N-...  Read full blog post.

TRIF/TICAM1 and mitochondrial dynamics in the innate immune response
TRIF, also known as toll like receptor adaptor molecule 1 or TICAM1, is known for its role in invading foreign pathogens as part of our innate immune response. TRIF/TICAM1 is a TIR-domain adaptor protein (toll/interleukin-1 receptor) that interacts...  Read full blog post.

MHC Class I and the Herpes Simplex Virus
MHC molecules (also known as major histocompatibility complex molecules) assist in the presentation of antigens to T cells in order to eradicate foreign pathogens.  These molecules are highly polymorphic, meaning that they exist in multiple varian...  Read full blog post.

The role of TLR4 in breast cancer
Toll like receptors (TLRs) are highly conserved proteins that are first known for their role in pathogen recognition and immune response activation.  In order to elicit the necessary immune response in reaction to a foreign pathogen, TLRs trigger cy...  Read full blog post.

TLR2 - I can recognize many foreign pathogens!
TLR2 is a member of the broad family of Toll-like receptors (TLR) that play an important role in pathogen recognition and innate immunity. TLRs, like other pattern recognition receptors (PRRs), recognize endogenous ligands released during cell or tiss...  Read full blog post.

IRAK4: The "master IRAK" critical for initiating immune responses
IRAK4, also known as Interleukin-1 receptor-associated kinase 4, is a serine/threonine-protein kinase that plays a critical role in initiating innate and adaptive immune responses against foreign pathogens. It activates NF-kappaB in both Toll-like rec...  Read full blog post.

TLR1
TLR1 belongs to the Toll-like receptor (TLR) family, and is a key player in the recognition of pathogens as well as the activation of the innate immunity system. TLRs are highly conserved proteins with a high degree of structural and functional homolo...  Read full blog post.

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Bioinformatics

Gene Symbol TLR2
Entrez