TLR1 Cell Lysate

Images

 
Western Blot: TLR1 Cell Lysate [NBP2-25064] - analysis of TLR1 in A) Ramos, B) RAW, and C) transfected HEK293 cell lysate (10 ul per lane) probed with 2 ug/ml of TLR1.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

TLR1 Cell Lysate Summary

Immunogen
Human TLR1 transfected cell lysate
Gene
TLR1

Applications/Dilutions

Application Notes
HEK293 cells were transfected with full-length human TLR1. Load 10 ul/lane of a mini-gel. This transfected cell lysate can be used as a positive western blot control for, anti-TLR1.

Packaging, Storage & Formulations

Storage
Store at -80C in the dark. Avoid freeze-thaw cycles.
Buffer
1 x SDS sample buffer: 60 mM Tris-Hcl (pH 6.8) 10 mM EDTA 2 % SDS 0.03% Bromophenol Blue 10% glycerol 0.3% Beta-mercaptoethanol

Lysate Details for Array

Type
Cell

Alternate Names for TLR1 Cell Lysate

  • CD281 antigen
  • CD281
  • DKFZp547I0610
  • DKFZp564I0682
  • KIAA0012MGC126311
  • MGC104956
  • MGC126312
  • rsc786
  • TIL
  • TIL. LPRS5
  • TLR1
  • Toll/interleukin-1 receptor-like protein
  • toll-like receptor 1

Background

The Toll-like receptor (TLR) family in mammals are comprised of a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an IL-1 receptor motif in the cytoplasmic domain. The TLRs could constitute an important and unrecognized component of innate immunity in humans. In mice, TLR1 interacts with TLR2 and coexpression of TLR1 and TLR2 enhance the NF-kappaB activation in response to a synthetic lipopeptide. They recognize the lipid configuration of the native mycobacterial lipoprotein as well as several triacylated lipopeptides.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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NBP2-25064
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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for TLR1 Lysate (NBP2-25064) (0)

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Other Available Formats

NBP2-25064

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Toll-like receptor 2 activation contributes to oral squamous cell carcinoma development and miRNA-mediated drug resistance
By Jamshed Arslan, Pharm. D., PhD. Squamous cell carcinoma is the most common cancer in the oral cavity.1 The tumor surface biofilms in oral cancers contain high levels of aerobic and anaerobic microorganisms.1,2 Peri...  Read full blog post.

The role of STING/TMEM173 in gamma and encephalitis Herpes Simplex Virus (HSV)
Stimulator of interferon genes (STING), also known as TMEM173, promotes the production of the interferon’s IFN-alpha and IFN-beta.  STING possesses three functional domains: a cytoplasmic C-terminal tail, a central globular domain, and four N-...  Read full blog post.

TLR1
TLR1 belongs to the Toll-like receptor (TLR) family, and is a key player in the recognition of pathogens as well as the activation of the innate immunity system. TLRs are highly conserved proteins with a high degree of structural and functional homolo...  Read full blog post.

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Bioinformatics

Gene Symbol TLR1