TLR1 Antibody

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Western Blot: TLR1 Antibody [NB110-86979] - Lane 1: mouse spleen tissue whole cell lysate using 1.0ug/mL. Lane 2: mouse spleen tissue whole cell lysate using 2.0ug/mL. Lane 3: mouse spleen tissue whole cell lysate using ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB110-86979
    • Availability
      Product Discontinued

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TLR1 Antibody Summary

Immunogen
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the amino terminus of human toll-like receptor 1 (TLR1) protein.
Specificity
This IgG fraction is directed against human TLR1 protein. This is reactive with TLR1 from human and mouse sources.
Clonality
Polyclonal
Host
Rabbit
Gene
TLR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1-4 ug/ml
  • ELISA 1:10000-1:40000
  • Immunohistochemistry 10 ug/ml
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
Expect a band at ~90 kDa in size corresponding - TLR1 by western blotting in the appropriate cell lysate or extract.
Positive Control
TLR1 Lysate (NBL1-16950)

Reactivity Notes

This antibody is reactive to Human and Mouse.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative
0.02% Sodium Azide
Concentration
LYOPH
Purity
Immunogen affinity purified
Reconstitution Instructions
Reconstitute with 50 ul of distilled water to a final concentration of 1.0 mg/ml.

Alternate Names for TLR1 Antibody

  • CD281 antigen
  • CD281
  • DKFZp547I0610
  • DKFZp564I0682
  • KIAA0012MGC126311
  • MGC104956
  • MGC126312
  • rsc786
  • TIL
  • TIL. LPRS5
  • TLR1
  • Toll/interleukin-1 receptor-like protein
  • toll-like receptor 1

Background

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells where they form heterodimers that can recognize triacylated lipoproteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for TLR1 Antibody (NB110-86979)

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Research Areas for TLR1 Antibody (NB110-86979)

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Blogs on TLR1.

The role of STING/TMEM173 in gamma and encephalitis Herpes Simplex Virus (HSV)
Stimulator of interferon genes (STING), also known as TMEM173, promotes the production of the interferon’s IFN-alpha and IFN-beta.  STING possesses three functional domains: a cytoplasmic C-terminal tail, a central globular domain, and four N-...  Read full blog post.

TLR1
TLR1 belongs to the Toll-like receptor (TLR) family, and is a key player in the recognition of pathogens as well as the activation of the innate immunity system. TLRs are highly conserved proteins with a high degree of structural and functional homolo...  Read full blog post.

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Bioinformatics

Gene Symbol TLR1
Entrez