IHC: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user. High temperature treatment of formalin-fixed tissue sections with 10mM citrate buffer, pH 6.0 must be performed prior to the immunostaining.
Cross-reacts with Human, Rabbit and Baboon. Not yet tested in other species.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Protein A purified
Alternate Names for TIMP-3 Antibody
metalloproteinase inhibitor 3
TIMP metallopeptidase inhibitor 3
tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy
Tissue inhibitor of metalloproteinases 3
TIMPs form tight inhibitory complexes with MMPs, which are involved in matrix degradation and in tumor invasiveness and metastasis. TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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