TIMP-3 Antibody

Images

 
Immunohistochemistry-Paraffin: TIMP3 Antibody [NB110-1483] - Formalin fixed paraffin embedded human breast carcinoma stained with TIMP-3 antibody.

Product Details

Summary
Product Discontinued
View other related TIMP-3 Primary Antibodies

Order Details


    • Catalog Number
      NB110-1483
    • Availability
      Product Discontinued

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TIMP-3 Antibody Summary

Immunogen
A synthetic peptide derived from the C-terminus region of human.
Localization
Secreted
Specificity
This reacts with a 23 kDa protein, known as TIMP 3.
Clonality
Polyclonal
Host
Rabbit
Gene
TIMP3
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
IHC: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user. High temperature treatment of formalin-fixed tissue sections with 10mM citrate buffer, pH 6.0 must be performed prior to the immunostaining.
Positive Control
TIMP-3 Lysate (NBL1-16926)
Publications
Read Publications using
NB110-1483 in the following applications:

Reactivity Notes

Cross-reacts with Human, Rabbit and Baboon. Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
Sodium Azide
Purity
Protein A purified

Alternate Names for TIMP-3 Antibody

  • HSMRK222
  • K222
  • K222TA2
  • metalloproteinase inhibitor 3
  • MIG-5 protein
  • Protein MIG-5
  • pseudoinflammatory)
  • SFD
  • TIMP metallopeptidase inhibitor 3
  • TIMP3
  • TIMP-3
  • tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy
  • Tissue inhibitor of metalloproteinases 3

Background

TIMPs form tight inhibitory complexes with MMPs, which are involved in matrix degradation and in tumor invasiveness and metastasis. TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TIMP-3 Antibody (NB110-1483)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.


Filter By Application
IHC-P
(1)
All Applications
Filter By Species
Human
(1)
All Species

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Product General Protocols

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FAQs for TIMP-3 Antibody (NB110-1483) (0)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional TIMP-3 Products

Bioinformatics Tool for TIMP-3 Antibody (NB110-1483)

Discover related pathways, diseases and genes to TIMP-3 Antibody (NB110-1483). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TIMP-3 Antibody (NB110-1483)

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Pathways for TIMP-3 Antibody (NB110-1483)

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Research Areas for TIMP-3 Antibody (NB110-1483)

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Blogs on TIMP-3

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Contact Information

Product PDFs

Calculators

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Bioinformatics

Gene Symbol TIMP3
Entrez