TIMP-2 Antibody

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Western Blot: TIMP-2 Antibody [NB100-92000] - Analysis of TIMP2 (A47) pAb in extracts from A549 cells.
Western Blot: TIMP-2 Antibody [NB100-92000] - Analysis of TIMP2 (A47) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264.7 whole cell lysateLane3:H9C2 whole cell lysate

Product Details

Summary
Product Discontinued
View other related TIMP-2 Primary Antibodies

Order Details


    • Catalog Number
      NB100-92000
    • Availability
      Product Discontinued

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TIMP-2 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 10-60 of Human TIMP-2.
Clonality
Polyclonal
Host
Rabbit
Gene
TIMP2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of TIMP2 (A47) pAb in extracts from A549 cells.
Theoretical MW
24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Positive Control
TIMP-2 Lysate (NBL1-16925)
Publications
Read Publications using
NB100-92000 in the following applications:

  • WB
    2 publications

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TIMP-2 Antibody

  • CSC-21Ktissue inhibitor of metalloproteinase 2
  • metalloproteinase inhibitor 2
  • TIMP metallopeptidase inhibitor 2
  • TIMP2
  • TIMP-2
  • Tissue inhibitor of metalloproteinases 2

Background

TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases, vgelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 was found to be identical to EPA (erythroidpotentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TIMP-2 Antibody (NB100-92000)(2)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: WB.


Filter By Application
WB
(2)
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Filter By Species
Human
(1)
Mouse
(1)
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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TIMP-2 Antibody (NB100-92000) (0)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional TIMP-2 Products

Bioinformatics Tool for TIMP-2 Antibody (NB100-92000)

Discover related pathways, diseases and genes to TIMP-2 Antibody (NB100-92000). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for TIMP-2 Antibody (NB100-92000)

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Pathways for TIMP-2 Antibody (NB100-92000)

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PTMs for TIMP-2 Antibody (NB100-92000)

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Research Areas for TIMP-2 Antibody (NB100-92000)

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Blogs on TIMP-2

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Contact Information

Product PDFs

Calculators

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Bioinformatics

Gene Symbol TIMP2
Entrez
Uniprot