TIMP-2 Antibody (1A6)

Images

 
Western Blot: TIMP2 Antibody (1A6) [NBP2-01573] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TIMP2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates ...read more
Immunohistochemistry-Paraffin: TIMP2 Antibody (1A6) [NBP2-01573] - Staining of paraffin-embedded Human pancreas tissue using anti-TIMP2 mouse monoclonal antibody.
Flow Cytometry: TIMP2 Antibody (1A6) [NBP2-01573] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-TIMP2 antibody, and then analyzed ...read more
Immunohistochemistry-Paraffin: TIMP2 Antibody (1A6) [NBP2-01573] - Staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-TIMP2 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: TIMP2 Antibody (1A6) [NBP2-01573] - Staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TIMP2 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: TIMP2 Antibody (1A6) [NBP2-01573] - Staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TIMP2 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: TIMP2 Antibody (1A6) [NBP2-01573] - Staining of paraffin-embedded Carcinoma of Human lung tissue using anti-TIMP2 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: TIMP2 Antibody (1A6) [NBP2-01573] - Staining of paraffin-embedded Human breast tissue using anti-TIMP2 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: TIMP2 Antibody (1A6) [NBP2-01573] - Staining of paraffin-embedded Human endometrium tissue using anti-TIMP2 mouse monoclonal antibody.
Flow Cytometry: TIMP2 Antibody (1A6) [NBP2-01573] - Analysis of Jurkat cells, using anti-TIMP2 antibody, (Red), compared to a nonspecific negative control antibody (Blue).

Product Details

Summary
Reactivity Hu, Mu, Rt, Ca, PmSpecies Glossary
Applications WB, Flow, IHC, IHC-P
Clone
1A6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

TIMP-2 Antibody (1A6) Summary

Immunogen
Full length human recombinant protein of human TIMP2(NP_003246) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TIMP2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-2000
  • Flow Cytometry 1:100
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin 1:150

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TIMP-2 Antibody (1A6)

  • CSC-21Ktissue inhibitor of metalloproteinase 2
  • metalloproteinase inhibitor 2
  • TIMP metallopeptidase inhibitor 2
  • TIMP2
  • TIMP-2
  • Tissue inhibitor of metalloproteinases 2

Background

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TIMP2
Entrez