TIMP-1 Native Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE, HPLC

Order Details

TIMP-1 Native Protein Summary

Description
A non-recombinant protein corresponding to 184 amino acids of Human TIMP-1
Preparation
Method
>92% SDS-PAGE
Protein/Peptide Type
Native Protein
Gene
TIMP1
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
50 mM Tris-HCl, pH 7; 200 mM NaCl; 5 mM CaCl2; 1 uM ZnCl2; 0.05% Brij 35
Preservative
0.05% Sodium Azide
Purity
>90%, by SDS-PAGE

Alternate Names for TIMP-1 Native Protein

  • CLGI
  • Collagenase inhibitor
  • collagenase inhibitor)
  • EPATIMP-1
  • EPO
  • erythroid potentiating activity
  • Erythroid-potentiating activity
  • Fibroblast collagenase inhibitor
  • FLJ90373
  • HCI
  • metalloproteinase inhibitor 1
  • TIMP metallopeptidase inhibitor 1
  • TIMP1
  • TIMP-1
  • TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
  • Tissue inhibitor of metalloproteinases 1

Background

The tissue inhibitor of metalloproteinases (TIMP-1) is a glycoprotein with a molecular mass of about 28-kDa. The secreted protein consists of 184 amino acids, six disuilfide bonds and two glycosylation sites containing N-linked oligosaccharides. TIMP-1 specifically inhibits the extracellular-matrix-egradingmetalloproteinases such as collagenase, gelatinase and stromelysin. It has no activity on mammalian membrane metallo-proteinases, procollagenpeptidase, or on bacterial metalloproteinases such as thermolysin

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics Tool for TIMP-1 Native Protein (NBP1-99910)

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Bioinformatics

Gene Symbol TIMP1
Entrez