TIMP-1 Antibody Summary
A synthetic peptide, which represented a portion of human Tissue Inhibitor of Metalloproteinase 1 encoded by exon 6 (LocusLink ID 7076).
This is specific for human TIMP1.
Primate (100%), Monkey (100%)
Immunogen affinity purified
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Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Tris-citrate/phosphate buffer, pH 7 to 8
0.09% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified
Western blot (reducing and non-reducing SDS-PAGE).
Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Rhesus Monkey, Gorilla, Yellow baboon, African elephant, Small-eared galago and Northern white-cheeked gibbon.
Alternate Names for TIMP-1 Antibody
- Collagenase inhibitor
- collagenase inhibitor)
- erythroid potentiating activity
- Erythroid-potentiating activity
- Fibroblast collagenase inhibitor
- metalloproteinase inhibitor 1
- TIMP metallopeptidase inhibitor 1
- TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
- Tissue inhibitor of metalloproteinases 1
Tissue inhibitor of metalloproteinases 1 (TIMP1) and Tissue inhibitor of metalloproteinases 2 (TIMP 2) have similar properties, specifically in inhibiting enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP1 forms a complex of 1:1 stoichiometry with activated interstitial collagenases, activated stromelysin, active form of 72kDa Type IV collagenase (also known as MMP2 or gelatinase A), and latent and active forms 92kDa Type IV collagenase (also known as MMP0 or gelatinase B). TIMPs inhibit the proteolytic invasiveness of tumour cells and normal placental trophoblast cells. TIMP1 is produced in low (pg/ml) levels by most cell types. Treatment of cells with the phorbol ester TPA stimulates production of TIMP1 in some cell types, but the low protein levels produced often require concentration of cell culture media to visualize the bands by Western Blotting.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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Positive Control Lysate(s)
Additional TIMP-1 Antibody Products
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, MATRIX METALLOPROTEINASE 3
, MATRIX METALLOPROTEINASE 9
, TISSUE INHIBITOR OF METALLOPROTEINASE-1
Bioinformatics Tool for TIMP-1 Antibody (NB100-283)
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Blogs on TIMP-1