TIM-3 Antibody (RM0135-6F46)

Images

 
There are currently no images for TIM-3 Antibody (NBP1-22511).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clone
RM0135-6F46
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

TIM-3 Antibody (RM0135-6F46) Summary

Immunogen
Mouse recombinant protein of TIM-3
Specificity
This was produced from a hybridoma (mouse myeloma) fused with spleen cells from a rat immunized with mouse recombinant protein of TIM-3.
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
HAVCR2
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
This antibody detects mouse of TIM-3 in Western blotting. This antibody does not cross-react with mouse TIM-1 and TIM-2.

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
A 0.2 um filtered solution in PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein G purified
Reconstitution Instructions
Reconstitute with 0.2 ml sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for TIM-3 Antibody (RM0135-6F46)

  • CD366
  • FLJ14428
  • HAVCR2
  • HAVcr-2
  • hepatitis A virus cellular receptor 2
  • kidney injury molecule-3
  • T cell immunoglobulin mucin 3
  • T cell immunoglobulin mucin-3
  • T-cell immunoglobulin and mucin domain-containing protein 3
  • TIM 3
  • TIM3 T-cell membrane protein 3
  • TIM3
  • TIM-3
  • TIMD-3
  • TIMD3KIM-3

Background

TIM 3 is a transmembrane protein expressed at high levels on Th1 lymphocytes and CD11b+ macrophages. TIM 3 has also been shown to exist as a soluble protein. Cells expressing TIM 3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim 3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF2045
Species: Hu
Applications: WB, IHC, ICC
NBP1-76701
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NBP1-19371
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
AF1086
Species: Hu
Applications: WB, Flow, IHC, Block, CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta)
NB100-40853
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBP1-23000
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
AF-386-PB
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC
NBP1-31470
Species: Hu, Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
NBP1-49045
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, CyTOF-ready, InhibTFunc
MAB7158
Species: Hu, Mu
Applications: WB, IHC
H00003117-M01
Species: Hu
Applications: WB, ELISA, PLA
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
NB100-39002
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP

Publications for TIM-3 Antibody (NBP1-22511) (0)

There are no publications for TIM-3 Antibody (NBP1-22511).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for TIM-3 Antibody (NBP1-22511) (0)

There are no reviews for TIM-3 Antibody (NBP1-22511). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for TIM-3 Antibody (NBP1-22511) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional TIM-3 Products

Bioinformatics Tool for TIM-3 Antibody (NBP1-22511)

Discover related pathways, diseases and genes to TIM-3 Antibody (NBP1-22511). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TIM-3 Antibody (NBP1-22511)

Discover more about diseases related to TIM-3 Antibody (NBP1-22511).
 

Pathways for TIM-3 Antibody (NBP1-22511)

View related products by pathway.

PTMs for TIM-3 Antibody (NBP1-22511)

Learn more about PTMs related to TIM-3 Antibody (NBP1-22511).
 

Research Areas for TIM-3 Antibody (NBP1-22511)

Find related products by research area.

Blogs on TIM-3.

TIM-3, a critical immune checkpoint in HIV research
CD4+ T-helper cells (Th) are the white blood lymphocytes expressing surface glycoprotein antigen CD4. These T-helper cells play an important role in the adaptive immune system by releasing T cell cytokines that help other immune cells to suppress o...  Read full blog post.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our TIM-3 Antibody (RM0135-6F46) and receive a gift card or discount.

Bioinformatics

Gene Symbol HAVCR2
Entrez
Uniprot