TIGAR/C12orf5 Antibody

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Immunohistochemistry: TIGAR Antibody [NBP1-71965]-FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-TIGAR used at a dilution of 1:250.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-71965
    • Availability
      Product Discontinued

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TIGAR/C12orf5 Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 220 and 270 of human TP53-induced glycolysis and apoptosis regulator using the numbering given in entry NP_065108.1 (GeneID 57103).
Clonality
Polyclonal
Host
Rabbit
Gene
C12ORF5
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TIGAR/C12orf5 Antibody

  • C12orf5
  • chromosome 12 open reading frame 5
  • EC 3.1.3.46
  • probable fructose-2,6-bisphosphatase TIGAR
  • TIGAR
  • TIGARTP53-induced glycolysis and apoptosis regulator
  • transactivated by NS3TP2 protein

Background

TIGAR (TP53-induced glycolysis and apoptosis regulator) is a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. TIGAR functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of TIGAR also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. [from NCBI GeneID: 57103]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol C12ORF5
Entrez
Uniprot