Recombinant Human Thyroid Peroxidase Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE, Bioactivity
Concentration
Lyoph

Order Details

Recombinant Human Thyroid Peroxidase Protein Summary

Description
Recombinant bioactive protein for Human Thyroid Peroxidase

Source:E. coli
Amino Acid Sequence:(P07202)

Preparation
Method
Determined to be >98% pure by SDS-PAGE
Details of Functionality
The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found <1 ng/ml, corresponding to a specific activity of >1 x 106 IU/mg.
Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
TPO
Purity
>95%, by SDS-PAGE
Endotoxin Note
<0.1 ng/ug

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
Lyophilized with no additives
Concentration
Lyoph
Purity
>95%, by SDS-PAGE
Reconstitution Instructions
Reconstitution in purified H2O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers andstored at 4C for 1 week or -20C for long-term storage. For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA).

Alternate Names for Recombinant Human Thyroid Peroxidase Protein

  • EC 1.11.1
  • MSA
  • TDH2A
  • thyroid microsomal antigen
  • thyroid peroxidase
  • thyroperoxidase
  • TPXEC 1.11.1.8

Background

TPO (Thrombopoietin, also known as Mpl-ligand, MGDF) stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant human TPO is a fully biologically active 174 amino acid polypeptide, which contains the erythropoietin-like domain of the full length TPO protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol TPO