Thymopoietin/LAP2 Antibody (RL29)


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Product Details

Reactivity RtSpecies Glossary
Applications WB, ICC/IF, IP
Armenian Hamster
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Thymopoietin/LAP2 Antibody (RL29) Summary

Pore complex-lamina fraction isolated from rat liver nuclear envelopes.
Nuclear and Secreted
Inner-nuclear Membrane Marker
Detects Lamin Associated Polypeptide (LAP) 2 from various rat tissues but does not cross-react with LAP 1A, 1B & 1C.This recognizes a single 53 kDa protein representing LAP 2 in rat liver nuclear envelope fractions.
Armenian Hamster
Protein A or G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
0.05% Sodium Azide
Protein A or G purified


  • Western Blot 1:1
  • Immunocytochemistry/Immunofluorescence 1:100000
  • Immunoprecipitation 1:10-1:500
Application Notes
Immunofluorescence: use at 1:100 Immunoprecipitation: Assay dependentWestern Blot: use at 1:1000Optimal dilutions should be determined by the individual.

Reactivity Notes

Cross-reacts with Rat.Not yet tested in other species.

Alternate Names for Thymopoietin/LAP2 Antibody (RL29)

  • CMD1T
  • lamina-associated polypeptide 2
  • LAP2PRO0868
  • LEM domain containing 4
  • LEMD4
  • MGC61508
  • Thymopoietin isoform alpha
  • thymopoietin
  • Thymopoietin, isoforms beta/gamma
  • Thymopoietin-related peptide isoform alpha
  • Thymopoietin-related peptide isoforms beta/gamma
  • TMPO
  • TP alpha
  • TP beta/gamma
  • TP
  • TPRP isoform alpha
  • TPRP isoforms beta/gamma


In eukaryotic cells, the nuclear envelope consists of inner and outer membranes which define the border between the nucleus and cytoplasm. The inner and outer nuclear membranes are joined by large, supramolecular assemblies called nuclear pore complexes through which various molecules pass into and out of the nucleus. The inner membrane is lined by a filamentous meshwork called the nuclear lamina made up of proteins called lamins. The attachment of the lamins to the inner nuclear membrane appears to occur through their association with 4 related integral membrane proteins called Lamin Associated Polypeptides (LAPs). LAP 1A, 1B & 1C share a high degree of sequence homology while LAP 2 is distinct from the others. LAP 1A & B bind lamins A, C and B1, while LAP 2 binds lamin B1 only. In addition to lamin binding, LAP 2 has been shown to bind to chromosomes. Phosphorylation of LAP 2 during mitosis inhibits binding to both lamins and chromosomes suggesting that LAP 2 plays an important role in nuclear envelope re-assembly.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Thymopoietin/LAP2 Antibody (NB120-2738) (0)

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NB120-2738AF405
Alexa Fluor (R) 488 Labeled NB120-2738AF488
Alexa Fluor (R) 647 Labeled NB120-2738AF647
Alexa Fluor (R) 700 Labeled NB120-2738AF700
Allophycocyanin Labeled NB120-2738APC
DyLight 350 Labeled NB120-2738UV
DyLight 405 Labeled NB120-2738V
DyLight 405LS Labeled NB120-2738V3
DyLight 488 Labeled NB120-2738G
DyLight 680 Labeled NB120-2738FR
DyLight 755 Labeled NB120-2738IR
PE Labeled NB120-2738PE
PerCP Labeled NB120-2738PCP

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Contact Information

Product PDFs


Gene Symbol TMPO

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