Thromboxane A2 R/TBXA2R Antibody

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Immunohistochemistry-Paraffin: Thromboxane A2 R/TBXA2R Antibody [NBP1-40198] - Staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-40198
    • Availability
      Product Discontinued

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Thromboxane A2 R/TBXA2R Antibody Summary

Immunogen
A synthetic peptide corresponding to amino acids 323 - 343 within the C-terminal of human thromboxane A2 receptor (TP Receptor).
Specificity
Recognizes human TP Receptor. Species cross-reactivity: Mouse, rat and Cos-7 (African green monkey).
Clonality
Polyclonal
Host
Rabbit
Gene
TBXA2R
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 3 ug/ml
  • Immunocytochemistry/Immunofluorescence 2 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
Theoretical MW
37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Concentration
LYOPH
Purity
Immunogen affinity purified
Reconstitution Instructions
1 ea 500 ul sterile ddH2O

Alternate Names for Thromboxane A2 R/TBXA2R Antibody

  • BDPLT13
  • Prostanoid TP Receptor
  • TBXA2R
  • Thromboxane A2 R
  • thromboxane A2 receptor
  • Thromboxane A2R
  • TP
  • TXA2-R
  • TXA2R2

Background

The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily. TBXA2R performs an essential role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation. Thromboxane A2 has been implicated in myocardial infarct, stroke, and asthma. Additionally, thromboxane-prostanoid receptors have been implicated in the pathogenesis of cardiovascular diseases. Changes in TBXA2R function have also been linked to a hereditary bleeding disorder. The thromboxane A2 receptor is encoded by a single gene that is alternatively spliced at the carboxyl terminus, resulting in two variants, TP (343 residues) and TP (407 residues) that share the first 328 amino acids.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Thromboxane A2 R/TBXA2R Antibody (NBP1-40198). (Showing 1 - 1 of 1 FAQ).

  1. I am wondering if this antibody allows users the ability to determine the splice variants via Western blot migration pattern?
    • This antibody was raised against amino acids 323-343 of human thromboxane A2. If the splice variants you refer to include this portion of the full length protein then this antibody should detect them.

Secondary Antibodies

 

Isotype Controls

Additional Thromboxane A2 R/TBXA2R Products

Bioinformatics Tool for Thromboxane A2 R/TBXA2R Antibody (NBP1-40198)

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Diseases for Thromboxane A2 R/TBXA2R Antibody (NBP1-40198)

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PTMs for Thromboxane A2 R/TBXA2R Antibody (NBP1-40198)

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Bioinformatics

Gene Symbol TBXA2R
Entrez
Uniprot