Thimet Oligopeptidase/THOP1 Antibody

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Western Blot: Thimet Oligopeptidase Antibody [NBP1-31547] - Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE, antibody diluted at 1:5000.

Product Details

Summary
Reactivity Hu, Mu, PoSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.93 mg/ml

Order Details

Thimet Oligopeptidase/THOP1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Thimet Oligopeptidase. The exact sequence is proprietary.
Localization
Cytoplasm
Predicted Species
Mouse (90%), Porcine (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
THOP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:10000
Theoretical MW
79 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Rat (89%) and Bovine (89%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.93 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Thimet Oligopeptidase/THOP1 Antibody

  • EC 3.4.24
  • EC 3.4.24.15
  • Endopeptidase 24.15
  • EP24.15
  • MEPD_HUMAN
  • MP78
  • thimet oligopeptidase 1
  • thimet oligopeptidase
  • THOP1
  • TOP

Background

A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enxymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Thimet Oligopeptidase/THOP1 Antibody (NBP1-31547) (0)

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol THOP1
Entrez