TGR5/GPBAR1 Antibody

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Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NLS1935] - Analysis of anti-GPBAR1 antibody with human uterus, endometrium.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NLS1935
    • Availability
      Product Discontinued

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TGR5/GPBAR1 Antibody Summary

Immunogen
Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human TGR5.
Epitope
3rd cytoplasmic domain of human
Specificity
Human TGR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (94%), Monkey (94%), Rabbit (94%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
GPBAR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 9 ug/ml
Positive Control
TGR5/GPBAR1 Lysate (NBL1-11217)

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%), Mouse (89%), Rat (89%), Bovine (89%), Hamster (89%), Elephant (89%), Equine (89%), Opossum (89%), Canien (83%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
0.87 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TGR5/GPBAR1 Antibody

  • BG37
  • BG37hBG37
  • G protein-coupled bile acid receptor 1
  • GPBA
  • GPBAR1
  • GPCR19
  • GPR131
  • G-protein coupled bile acid receptor 1
  • G-protein coupled bile acid receptor BG37
  • G-protein coupled receptor GPCR19
  • M-BAR
  • M-BARhGPCR19
  • membrane bile acid receptor
  • Membrane-type receptor for bile acids
  • MGC40597
  • TGR5
  • TGR5GPCR

Background

BG37/TGR5 is the first Bile Acid GPCR to be identified. BG37/TGR5 expression has been reported in a wide variety of tissues, especially placenta, spleen, and monocyte/macrophages. ESTs have been isolated from blood, breast, and skin libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for TGR5/GPBAR1 Antibody (NLS1935)

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Research Areas for TGR5/GPBAR1 Antibody (NLS1935)

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Blogs on TGR5/GPBAR1.

The TGR5 Receptor and metabolic disease
The bile acid-responsive G-protein-coupled receptor TGR5 is widely distributed across the human body - including the endocrine glands, adipocyte cells, muscles, immune organs, spinal cord, and the enteric nervous system. G protein coupled receptor...  Read full blog post.

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Bioinformatics

Gene Symbol GPBAR1
Entrez