TGF-beta 1 Antibody (4F9C10) Summary
Purified recombinant fragment of TGFbeta1 expressed in E. Coli.
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Western Blot 1: 500 - 1:2000
- ELISA 1:10000
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.03% Sodium Azide
Alternate Names for TGF-beta 1 Antibody (4F9C10)
- latency-associated peptide
- TGF-beta 1 protein
- TGFbeta 1
- TGF-beta 1
- transforming growth factor beta-1
- transforming growth factor, beta 1
Transforming growth factor betas (TGFbetas) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFalpha. It is now realized that TGFbetas mediate many cell-cell interactions that occur during embryonic development. Three TGFbetas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFbeta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFbeta3 protein has approximately 80% identity to the mature region of both TGFbeta1 and TGFbeta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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