TERF2IP Antibody

Images

 
Western Blot: TERF21P Antibody [NBP1-49862] - (0.2ug/ml) staining of Human Tonsil lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-49862
    • Availability
      Product Discontinued

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TERF2IP Antibody Summary

Immunogen
Peptide with sequence C-GAQNVARRIEFRKK corresponding to C-Terminus according to NP_061848.2.
Epitope
GAQNVARRIEFRKK - C Terminus
Marker
Lysosome Marker
Clonality
Polyclonal
Host
Goat
Gene
TERF2IP
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 - 0.3 ug/ml
  • Peptide ELISA Detection limit 1:64000
Application Notes
WB: Approx. 60 kDa band observed in human bone marrow, lymph node and tonsil lysates (calculated MW of 44.3 kDa band according to NP_061848.2). The observed molecular weight corresponds to earlier findings with different antibodies from other sources.
Publications
Read Publication using NBP1-49862.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat, Bovine, Canine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TERF2IP Antibody

  • dopamine receptor interacting protein 5
  • Dopamine receptor-interacting protein 5
  • DRIP5
  • hRap1
  • RAP1 homolog
  • RAP1TERF2-interacting telomeric protein 1
  • Repressor/activator protein 1 homolog
  • telomeric repeat binding factor 2, interacting protein
  • telomeric repeat-binding factor 2-interacting protein 1
  • TRF2-interacting telomeric protein 1
  • TRF2-interacting telomeric RAP1 protein

Background

Rap1, also known as Krev-1 and smg p21, is a member of the Ras super family of GTPases closely related to Ras. Two known isoforms of Rap1 exists, Rap1A and Rap1B which share 95% identity (1-2). As a molecular switch, Rap1 cycles between two conformational states depending on whether GDP bound (active form) or GTP bound (inactive form). Rap1 associates with a subset of Ras effectors including Raf-1, B-Raf, phosphoinositide 3-kinase, Ral GEFs, and PLC (3). Although its function is still unclear, Rap1 has been shown to be involved in the regulation of integrin-mediated cell adhesion (4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TERF2IP Antibody (NBP1-49862)(1)


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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TERF2IP
Entrez
Uniprot