TCR delta/gamma Antibody (AP-MAB0864)

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
AP-MAB0864
Clonality
Monoclonal
Host
Armenian Hamster
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

TCR delta/gamma Antibody (AP-MAB0864) Summary

Immunogen
Mouse thymus
Specificity
TCR (delta/gamma)
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
TRA
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
  • CyTOF-ready
Application Notes
Flow cytometry as well as In vitro activation of γ/δ TCR-bearing T cells and In vivo depletion of peripheral gamma/ delta TCR-bearing T cells. Extremely low level of LPS (< 0.002EU/ug IgG)

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
A 0.2 um filtered solution in PBS - Azide free
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for TCR delta/gamma Antibody (AP-MAB0864)

  • C)
  • D
  • FLJ22602
  • J
  • MGC117436
  • MGC22624
  • MGC23964
  • MGC71411
  • T cell receptor alpha locus
  • T-cell antigen receptor, alpha polypeptide
  • T-cell receptor, alpha (V
  • TCRA
  • TCRD
  • TRA

Background

T cell receptor (TCR) is a heterodimer consisting of an alpha and a beta chain (TCR alpha/beta) or a gamma and a delta chain (TCR gamma/delta). TCR gamma/delta belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The gamma/delta TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most gamma/delta T cells are CD4-/CD8-, some are CD8+. T cells expressing the gamma/delta TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that gamma/delta T cells also play a principal role in antigen presentation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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TCR delta/gamma NBP1-06689

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Bioinformatics

Gene Symbol TRA
Entrez