Syntaxin 6 Antibody (3D10)

Product Discontinued

Syntaxin 6 Antibody (3D10) Summary

• Immunogen: Recombinant rat Syntaxin 6.
• Marker: TGN Marker
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: STX6
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 12ug/ml
  • Western Blot 1:1000
• Application Notes: This antibody is useful in Immunoprecipitation and detects a band of ~35kDa by Western blot.

Reactivity Notes

Human, Mouse, Rat and Hamster

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 50% Glycerol
• Preservative: 0.09% Sodium Azide
• Purity: Protein G purified

Alternate Names for Syntaxin 6 Antibody (3D10)

• STX6
• Syntaxin 6
• syntaxin-6

Background

Syntaxins are type II integral membrane proteins localized to membranes that regulate vesicle transport, protein maturation, and exocytosis. Syntaxin 1A resides in the nerve terminals of sensory neurons and nerve fibers reaching small blood vessels. Syntaxin 2 localizes to the apical plasma membrane and regulates epithelial-mesenchymal interactions. Syntaxin 6 is primarily localized to the trans-Golgi network, and partially co-localizes with AP-1 on clathrin-coated membranes. Syntaxin 13 is ubiquitously expressed and localizes to the tubular early and recycling endosomes, as well as endosomal vacuoles.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Syntaxin 6 Antibody (NBP1-97495)(3)

Publications using NBP1-97495

• HM Jack et al. Immunoglobulin mu heavy chains do not mediate tyrosine phosphorylation of Ig alpha from the ER-cis-Golgi. J. Immunol. 171, 3091 . 2003-01-01 [PMID: 12960335] (ICC/IF, Mouse)
• V Deretic et al. Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest. PNAS 100, 5437 . 2003-01-01 [PMID: 12702770] (WB, Mouse)
• DJ Selkoe et al. Complex N-linked glycosylated nicastrin associates with active gamma -secretase and undergoes tight cellular regulation. J. Biol. Chem. 277, 35113 . 2002-01-01 [PMID: 12130643] (WB, Human)

Bioinformatics

• Gene Symbol: STX6