Synapsin I Antibody

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Western Blot: Synapsin I Antibody [NB300-312] - Analysis of Synapsin I in rat hippocampal lysate using this antibody at 1:1000.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Synapsin I Antibody Summary

Immunogen
Native protein purified from bovine brain
Marker
pre-Synaptic Marker
Specificity
Specific for the ~78k synapsin I protein doublet. Immunolabeling blocked by preadsorption of the antibody with the protein used to generate the antibody.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SYN1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Immunocytochemistry/Immunofluorescence
Application Notes
Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 27849576).
Publications
Read Publication using NB300-312.

Reactivity Notes

Tested in Human, Mouse and Rat.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Neat whole antisera
Preservative
No Preservative
Purity
Unpurified

Alternate Names for Synapsin I Antibody

  • SYN1
  • SYN1a
  • SYN1b
  • Synapsin 1
  • Synapsin I
  • synapsin IBrain protein 4.1
  • synapsin-1
  • SYNI

Background

Synapsin I plays a key role in synaptic plasticity in the brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation. Thus Synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Synapsin I Antibody (NB300-312)(1)

We have publications tested in 1 application: ICC/IF.


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ICC/IF
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Blogs on Synapsin I.

Synapsin I, a pre-synaptic marker
Synapsin-I, also called Synapsin 1/Syn1, is an ~80 kDa protein (predicted mol. wt. 74.1 kDa) which belongs to the Synapsin family (Synapsin I, Synapsin II, Synapsin III). Synapsins are the evolutionarily conserved phospho-proteins which are associ...  Read full blog post.

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Bioinformatics

Gene Symbol SYN1
Entrez
Uniprot