SWAP70 Antibody (1A12)

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Immunocytochemistry/ Immunofluorescence: SWAP70 Antibody (1A12) [H00023075-M04] - Analysis of monoclonal antibody to SWAP70 on HeLa cell. Antibody concentration 10 ug/ml

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clone
1A12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

SWAP70 Antibody (1A12) Summary

Immunogen
SWAP70 (NP_055870, 378 a.a. ~ 452 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.QTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQA
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SWAP70
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
This antibody is useful for ELISA, Western Blot

Reactivity Notes

This product is reactive against Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SWAP70 Antibody (1A12)

  • KIAA0640SWAP-70FLJ39540
  • SWAP switching B-cell complex 70kDa subunit
  • SWAP70
  • switch-associated protein 70

Background

SWAP70 is a phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. In vitro, it functions as the only B cell-specific component of an immunoglobulin isotype switch recombination enzyme complex called SWAP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SWAP70
Entrez
Uniprot