STK4 Antibody


Western Blot: STK4 Antibody [NB100-92185] - Analysis of STK4 at 1:500 dilution. Lane 1 - HEK293T whole cell lysate, Lane 2 - Mouse spleen tissue lysate, Lane 3 - H9C2 whole cell lysate
Immunohistochemistry: STK4 Antibody [NB100-92185] - Analysis of STKA antibody in paraffin-embedded human breast carcinoma tissue.

Product Details

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STK4 Antibody Summary

Synthetic peptide, corresponding to amino acids 150-200 of Human MST1.
Immunogen affinity purified
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  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
Theoretical MW
65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Positive Control
STK4 Lysate (NBP2-66194)

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for STK4 Antibody

  • EC 2.7.11
  • EC
  • kinase responsive to stress 2
  • KRS2KRS2))
  • Mammalian STE20-like protein kinase 1
  • mammalian sterile 20-like 1
  • MST-1
  • MST1DKFZp686A2068
  • serine/threonine kinase 4
  • serine/threonine-protein kinase 4
  • Serine/threonine-protein kinase Krs-2
  • STE20-like kinase MST1


Sterile-20 (STE20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein coupled receptors to cytosolic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to STE20 are divided into two groups, the PAK subfamily and the GCK subfamily. The PAK subfamily members contain a C-terminal catalytic domain and an N-terminal regulatory domain with a p21Rac/Cdc42- binding site, and these kinases can activate both p38MAPK and JNK. The GCK subfamily members contain a C-terminal regulatory domain and an Nterminal catalytic domain, and they have diverse roles in many pathways, including the activation of ERK< JNK, p38 MAPK, and caspase-3. The mammalian STE20-like kinases (MST kinases, also known as Ksr proteins) are members of the GCK subfamily. Ksr-1 and Ksr-2 (also known as MST-2 and MST-1, respectively) are both direct substrates of caspase-3 that accelerate caspase-3 activation. MST-3 is ubiquitously expressed in mammalian tissue and can phosphorylate exogenous substrates as well as itself. MST-4 is highly expressed in placenta, thymus, and peripheral blood leukocytes, and it specifically activates ERK.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

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Gene Symbol STK4