STING/TMEM173 Antibody

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ELISA: STING/TMEM173/MPYS Antibody [44320002]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

STING/TMEM173 Antibody Summary

Immunogen
This antibody is specific for the C Terminus Region of the target protein.
Specificity
This product is specific for Human TMEM173/MPYS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TMEM173
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:5000-1:20000
  • ELISA 1:100-1:2000
Application Notes
This antibody is useful in ELISA and Western Blot.
Control
STING/TMEM173 Lysate (NBP2-66102)
Publications
Read Publications using 44320002.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for STING/TMEM173 Antibody

  • endoplasmic reticulum IFN stimulator
  • Endoplasmic reticulum interferon stimulator
  • ERIS
  • FLJ38577
  • hMITA
  • Mediator of IRF3 activation
  • MITA
  • mitochondrial mediator of IRF3 activation
  • MPYS
  • NET23
  • N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner
  • Stimulator of interferon genes protein
  • STING
  • STINGhSTING
  • TMEM173
  • transmembrane protein 173

Background

TMEM173/MPYS acts as a facilitator of innate immune signaling. TMEM173/MPYS is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for STING/TMEM173 Antibody (44320002)(2)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for STING/TMEM173 Antibody (44320002) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Diseases for STING/TMEM173 Antibody (44320002)

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Pathways for STING/TMEM173 Antibody (44320002)

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Blogs on STING/TMEM173.

STING in Innate Immunity and Cancer: What’s the Buzz About?
STING (STimulator of INterferon Genes protein) acts as a sensor of cytosolic DNA. Bacteria/Virus or self-derived DNA in the cytosol activates the STING pathway and promotes the production of type I interferons (IFN-alpha and IFN-beta). STING also...  Read full blog post.

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Bioinformatics

Gene Symbol TMEM173
Entrez
Uniprot