Stathmin 1 Antibody (SP49)

Images

 
Western Blot: Stathmin 1 Antibody (SP49) [NBP1-49812] - NIH3T3
Immunohistochemistry-Paraffin: Stathmin 1 Antibody (SP49) [NBP1-49812] - Human Tonsil
Immunohistochemistry-Paraffin: Stathmin 1 Antibody (SP49) [NBP1-49812] - Stathmin

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-P
Clone
SP49
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Stathmin 1 Antibody (SP49) Summary

Immunogen
A synthetic peptide derived from the internal region of human stathmin
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
STMN1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This product is useful for Immunohistochemistry Paraffin. Antigen retrieval can be performed using a Citrate process.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
7.0 ml prediluted antibody with 10mM PBS (pH 7.4) and 1.0% BSA
Preservative
Sodium Azide
Purity
Protein A or G purified

Notes

For a positive control use Colon carcinoma.

Alternate Names for Stathmin 1 Antibody (SP49)

  • C1orf215
  • chromosome 1 open reading frame 215
  • Lag
  • Leukemia-associated phosphoprotein p18
  • metablastin
  • MGC138869
  • Oncoprotein 18
  • Op18
  • OP18MGC138870
  • phosphoprotein 19
  • Phosphoprotein p19
  • PP17
  • PP19
  • PR22
  • prosolin
  • Protein Pr22
  • SMNLAP18FLJ32206
  • stathmin 1
  • stathmin 1/oncoprotein 18
  • stathmin
  • transmembrane protein C1orf215

Background

Stathmin/Op18 is a 19 kD member of the Stathmin family. This protein is localized in the cytoplasm and becomes nuclear during the S/G2 phase of the cell cycle. Stathmin/Op18 acts as a microtubule destabilizer in mitotic spindle regulation and sequesters tubulin dimers into assembly-incompetent complexes. This protein participates as an intracellular relay integrating regulatory signals of the cellular environment and has been shown to be involved in megakaryocyte polyploidization. Stathmin/Op18 can be phosphorylated in response to heat; Ser62 phosphorylation reduces tubulin binding ability. This protein can also be modified by acetylation. Stathmin/Op18 has been shown to interact with tubulin, KIST, CaM kinase II and IV, Cdc2, MAPK, and Cdk1. The Poly6202 antibody recognizes human phosphorylated stathmin/Op18 (Ser16) and has been shown to be useful for Western blotting.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol STMN1